Updates in Refractory Status Epilepticus
Joint Authors
Marawar, Rohit
Basha, Maysaa
Mahulikar, Advait
Desai, Aaron
Suchdev, Kushak
Shah, Aashit
Source
Critical Care Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-08
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Refractory status epilepticus is defined as persistent seizures despite appropriate use of two intravenous medications, one of which is a benzodiazepine.
It can be seen in up to 40% of cases of status epilepticus with an acute symptomatic etiology as the most likely cause.
New-onset refractory status epilepticus (NORSE) is a recently coined term for refractory status epilepticus where no apparent cause is found after initial testing.
A large proportion of NORSE cases are eventually found to have an autoimmune etiology needing immunomodulatory treatment.
Management of refractory status epilepticus involves treatment of an underlying etiology in addition to intravenous anesthetics and antiepileptic drugs.
Alternative treatment options including diet therapies, electroconvulsive therapy, and surgical resection in case of a focal lesion should be considered.
Short-term and long-term outcomes tend to be poor with significant morbidity and mortality with only one-third of patients reaching baseline neurological status.
American Psychological Association (APA)
Marawar, Rohit& Basha, Maysaa& Mahulikar, Advait& Desai, Aaron& Suchdev, Kushak& Shah, Aashit. 2018. Updates in Refractory Status Epilepticus. Critical Care Research and Practice،Vol. 2018, no. 2018, pp.1-19.
https://search.emarefa.net/detail/BIM-1130466
Modern Language Association (MLA)
Marawar, Rohit…[et al.]. Updates in Refractory Status Epilepticus. Critical Care Research and Practice No. 2018 (2018), pp.1-19.
https://search.emarefa.net/detail/BIM-1130466
American Medical Association (AMA)
Marawar, Rohit& Basha, Maysaa& Mahulikar, Advait& Desai, Aaron& Suchdev, Kushak& Shah, Aashit. Updates in Refractory Status Epilepticus. Critical Care Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-19.
https://search.emarefa.net/detail/BIM-1130466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130466