Theoretical Modeling of Long-Time Drug Release from Nitrosalicyl-Imine-Chitosan Hydrogels through Multifractal Logistic Type Laws
Joint Authors
Agop, Maricel
Craciun, Anda-Mihaela
Barhalescu, Mihaela Luminita
Ochiuz, Lăcrămioara
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-14
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Drug release is a complex phenomenon due to the large number of interdependent side effects that occur simultaneously, involving strong nonlinear dynamics.
Therefore, since their theoretical description is difficult in the classical mathematics modelling, we have built a theoretical model based on logistic type laws, validated by the correlations with the experimental data, in a special case of drug release from hydrogels.
The novelty of our approach is the implementation of multifractality in logistic type laws, situation in which any chaotic system, characterized by a small number of nonlinear interactions, gets memory and, implicitly, characterization through a large number of nonlinear interactions.
In other words, the complex system polymer-drug matrix becomes “pseudo-intelligent.”
American Psychological Association (APA)
Craciun, Anda-Mihaela& Barhalescu, Mihaela Luminita& Agop, Maricel& Ochiuz, Lăcrămioara. 2019. Theoretical Modeling of Long-Time Drug Release from Nitrosalicyl-Imine-Chitosan Hydrogels through Multifractal Logistic Type Laws. Computational and Mathematical Methods in Medicine،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1130558
Modern Language Association (MLA)
Craciun, Anda-Mihaela…[et al.]. Theoretical Modeling of Long-Time Drug Release from Nitrosalicyl-Imine-Chitosan Hydrogels through Multifractal Logistic Type Laws. Computational and Mathematical Methods in Medicine No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1130558
American Medical Association (AMA)
Craciun, Anda-Mihaela& Barhalescu, Mihaela Luminita& Agop, Maricel& Ochiuz, Lăcrămioara. Theoretical Modeling of Long-Time Drug Release from Nitrosalicyl-Imine-Chitosan Hydrogels through Multifractal Logistic Type Laws. Computational and Mathematical Methods in Medicine. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1130558
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130558