The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial
Joint Authors
Moro, Eduardo Toshiyuki
Ferreira, Miguel Antônio Teixeira
Gonçalves, Renyer dos Santos
Vargas, Roberta Costa
Calil, Samira Joverno
Soranz, Maria Alice
Bloomstone, Joshua
Source
Anesthesiology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-20
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Intrathecal morphine is widely and successfully used to prevent postoperative pain after orthopedic surgery, but it is frequently associated with side effects.
The aim of this study was to evaluate the effect of dexamethasone or ondansetron when compared to placebo to reduce the occurrence of these undesirable effects and, consequently, to improve the quality of recovery based on patient’s perspective.
Methods.
One hundred and thirty-five patients undergoing lower extremity orthopedic surgery under spinal anesthesia using bupivacaine and morphine were randomly assigned to receive IV dexamethasone, ondansetron, or saline.
On the morning following surgery, a quality of recovery questionnaire (QoR-40) was completed.
Results.
No differences were detected in the global and dimensional QoR-40 scores following surgery; however, following postanesthesia care unit (PACU) discharge, pain scores were higher in patients receiving ondansetron compared with patients who received dexamethasone.
Conclusion.
Neither ondansetron nor dexamethasone improves the quality of recovery after lower limbs orthopedic surgery under spinal anesthesia using intrathecal morphine.
American Psychological Association (APA)
Moro, Eduardo Toshiyuki& Ferreira, Miguel Antônio Teixeira& Gonçalves, Renyer dos Santos& Vargas, Roberta Costa& Calil, Samira Joverno& Soranz, Maria Alice…[et al.]. 2020. The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial. Anesthesiology Research and Practice،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1130565
Modern Language Association (MLA)
Moro, Eduardo Toshiyuki…[et al.]. The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial. Anesthesiology Research and Practice No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1130565
American Medical Association (AMA)
Moro, Eduardo Toshiyuki& Ferreira, Miguel Antônio Teixeira& Gonçalves, Renyer dos Santos& Vargas, Roberta Costa& Calil, Samira Joverno& Soranz, Maria Alice…[et al.]. The Quality of Recovery after Dexamethasone, Ondansetron, or Placebo Administration in Patients Undergoing Lower Limbs Orthopedic Surgery under Spinal Anesthesia Using Intrathecal Morphine. A Randomized Controlled Trial. Anesthesiology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1130565
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130565