A Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Fine-Needle Biopsy in the Diagnosis of Solid Pancreatic Lesions
Joint Authors
Kmiotek, Elizabeth K.
Lam, Eric
Ayres, Lachlan R.
Telford, Jennifer J.
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and Aims.
Endoscopic ultrasound (EUS) guided fine-needle aspiration (FNA) is the method of choice for sampling pancreatic lesions.
This study compares the diagnostic accuracy and safety of FNB using a novel core needle to FNA in solid pancreatic lesions.
Methods.
A retrospective review of patients in whom EUS FNA or FNB was performed for solid pancreatic lesions was conducted.
Diagnostic performance was calculated based upon a dual classification system: classification 1, only malignant pathology considered a true positive, versus classification 2, atypical, suspicious, and malignant pathology considered a true positive.
Results.
43 patients underwent FNB compared with 51 FNA.
Using classification 1, sensitivity was 74.0% versus 80.0%, specificity 100% versus 100%, and diagnostic accuracy 77.0% versus 80.0% for FNB versus FNA, respectively (all p>0.05).
Using classification 2, sensitivity was 97% versus 94.0%, specificity 100% versus 100%, and diagnostic accuracy 98.0% versus 94.0% for FNB versus FNA, respectively (all p>0.05).
FNB required significantly fewer needle passes (median = 2) compared to FNA (median = 3; p<0.001).
Adverse events occurred in two (4.5%) FNB patients compared with none in the FNA group (p>0.05).
Conclusion.
FNA and FNB have comparable sensitivity and diagnostic accuracy.
FNB required fewer passes.
American Psychological Association (APA)
Ayres, Lachlan R.& Kmiotek, Elizabeth K.& Lam, Eric& Telford, Jennifer J.. 2018. A Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Fine-Needle Biopsy in the Diagnosis of Solid Pancreatic Lesions. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1130873
Modern Language Association (MLA)
Ayres, Lachlan R.…[et al.]. A Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Fine-Needle Biopsy in the Diagnosis of Solid Pancreatic Lesions. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1130873
American Medical Association (AMA)
Ayres, Lachlan R.& Kmiotek, Elizabeth K.& Lam, Eric& Telford, Jennifer J.. A Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Fine-Needle Biopsy in the Diagnosis of Solid Pancreatic Lesions. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1130873
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130873