Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis
Joint Authors
Suetani, Keigo
Michikawa, Yosuke
Nakahara, Kazunari
Kobayashi, Shinjiro
Sato, Junya
Morita, Ryo
Morita, Nozomi
Itoh, Fumio
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background/Aims.
In early endoscopic retrograde cholangiopancreatography (ERCP) for acute cholangitis due to choledocholithiasis, it is unclear that single-session stone removal can be safely performed.
We examined the efficacy and safety of early single-session stone removal for mild-to-moderate acute cholangitis associated with choledocholithiasis.
Methods.
Among patients with mild-to-moderate acute cholangitis associated with choledocholithiasis who underwent early ERCP (n = 167), we retrospectively compared the removal group (patients who underwent single-session stone removal; n = 78) with the drainage group (patients who underwent biliary drainage alone; n = 89) and examined the effectiveness and safety of single-session stone removal by early ERCP.
Results.
The patients in the removal group had significantly fewer and smaller stones compared with those in the drainage group.
The single-session complete stone removal rate was 85.9% in the removal group.
The complication rate in early ERCP was 11.5% in the removal group and 10.1% in the drainage group, with no significant difference (P = 0.963).
On comparing patients who underwent early endoscopic sphincterotomy (EST) with those who underwent elective EST after cholangitis had improved, the post-EST bleeding rates were 6.8% and 2.7%, respectively, with no significant difference (P = 0.600).
The mean duration of hospitalization was 11.9 days for the removal group and 19.9 days for the drainage group, indicating a shorter stay for the removal group (P < 0.001).
In multiple linear regression analysis, stone removal in early ERCP, number of stones, and C-reactive protein level were significant predictors of hospitalization period.
Conclusions.
Single-session stone removal for mild-to-moderate acute cholangitis can be safely performed.
It is useful from the perspective of shorter hospital stay.
American Psychological Association (APA)
Sato, Junya& Nakahara, Kazunari& Morita, Ryo& Morita, Nozomi& Suetani, Keigo& Michikawa, Yosuke…[et al.]. 2018. Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1130895
Modern Language Association (MLA)
Sato, Junya…[et al.]. Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1130895
American Medical Association (AMA)
Sato, Junya& Nakahara, Kazunari& Morita, Ryo& Morita, Nozomi& Suetani, Keigo& Michikawa, Yosuke…[et al.]. Efficacy and Safety of Single-Session Endoscopic Stone Removal for Acute Cholangitis Associated with Choledocholithiasis. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1130895
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130895