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Mortality and Its Predictors among HIV Infected Patients Taking Antiretroviral Treatment in Ethiopia: A Systematic Review
Author
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
Even though the benefit of antiretroviral therapy (ART) is well established, there is a regional variation in the extent of its benefit.
The aim of this review is to highlight mortality and its predictors in Ethiopian adult HIV patients who were on ART.
Methods.
Relevant articles were searched on PubMed and Google Scholar databases.
The search terms used in different combinations were predictor/determinant/factors, mortality/death/survival, HIV, ART/HAART, and Ethiopia.
Result.
5–40.8% of the patients died during the follow-up period.
More than half (50–68.8%) of the deaths occurred within 6 months of initiating ART.
Advanced stage disease (stage III and stage IV), nonworking functional status (bedridden and ambulatory), low baseline CD4 count, low baseline hemoglobin level, TB coinfection, lower baseline weight, and poor treatment adherence were commonly identified as predictors of death in HIV patients.
Conclusion.
5–40.8% of HIV patients in Ethiopia die in 2–5 years of initiating antiretroviral treatment.
Most of the deaths in HIV patients occur early in the course of treatment.
Special emphasis should be given for patients with advanced stage disease, nonworking functional status, low baseline CD4 count, low baseline hemoglobin level, TB coinfection, lower baseline weight, and poor treatment adherence.
American Psychological Association (APA)
Biset Ayalew, Mohammed. 2017. Mortality and Its Predictors among HIV Infected Patients Taking Antiretroviral Treatment in Ethiopia: A Systematic Review. AIDS Research and Treatment،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1130934
Modern Language Association (MLA)
Biset Ayalew, Mohammed. Mortality and Its Predictors among HIV Infected Patients Taking Antiretroviral Treatment in Ethiopia: A Systematic Review. AIDS Research and Treatment No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1130934
American Medical Association (AMA)
Biset Ayalew, Mohammed. Mortality and Its Predictors among HIV Infected Patients Taking Antiretroviral Treatment in Ethiopia: A Systematic Review. AIDS Research and Treatment. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1130934
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1130934