The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients

Joint Authors

Sidorkiewicz, Malgorzata
Grek-Kowalinska, Martyna
Piekarska, Anna

Source

Canadian Journal of Gastroenterology and Hepatology

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-07-24

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases
Medicine

Abstract EN

Chronic HCV infection is strictly associated with host lipid/lipoprotein metabolism disorders.

The study aimed to analyze the relationship between viral load, lipid profile, IFNγ, and the expression of miR-122 and LPL in the liver and PBMCs.

Sera, PBMCs, and matching liver biopsies from 17 chronic hepatitis C patients were enrolled in this study.

Collected data shows that liver (not PBMCs) miR-122 expression is positively correlated with HCV RNA load and IFNγ and reversely with LPL expression in CHC patients.

Presented, for the first time, in this study, the reverse correlation of miR-122 and LPL expression in liver; miR-122 and LPL seem to be important factors of CHC infection.

American Psychological Association (APA)

Sidorkiewicz, Malgorzata& Grek-Kowalinska, Martyna& Piekarska, Anna. 2018. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1131000

Modern Language Association (MLA)

Sidorkiewicz, Malgorzata…[et al.]. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1131000

American Medical Association (AMA)

Sidorkiewicz, Malgorzata& Grek-Kowalinska, Martyna& Piekarska, Anna. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1131000

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1131000