The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients
Joint Authors
Sidorkiewicz, Malgorzata
Grek-Kowalinska, Martyna
Piekarska, Anna
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-24
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Chronic HCV infection is strictly associated with host lipid/lipoprotein metabolism disorders.
The study aimed to analyze the relationship between viral load, lipid profile, IFNγ, and the expression of miR-122 and LPL in the liver and PBMCs.
Sera, PBMCs, and matching liver biopsies from 17 chronic hepatitis C patients were enrolled in this study.
Collected data shows that liver (not PBMCs) miR-122 expression is positively correlated with HCV RNA load and IFNγ and reversely with LPL expression in CHC patients.
Presented, for the first time, in this study, the reverse correlation of miR-122 and LPL expression in liver; miR-122 and LPL seem to be important factors of CHC infection.
American Psychological Association (APA)
Sidorkiewicz, Malgorzata& Grek-Kowalinska, Martyna& Piekarska, Anna. 2018. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1131000
Modern Language Association (MLA)
Sidorkiewicz, Malgorzata…[et al.]. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1131000
American Medical Association (AMA)
Sidorkiewicz, Malgorzata& Grek-Kowalinska, Martyna& Piekarska, Anna. The Correlation between miR-122 and Lipoprotein Lipase Expression in Chronic Hepatitis C Patients. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1131000
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131000