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Addition of Ceftriaxone and Amikacin to a Ciprofloxacin plus Metronidazole Regimen for Preventing Infectious Complications of Transrectal Ultrasound-Guided Prostate Biopsy: A Randomized Controlled Trial
Joint Authors
Izadpanahi, Mohammad-Hossein
Nouri-Mahdavi, Kia
Majidi, Seyed Mahmood
Khorrami, Mohammad-Hatef
Alizadeh, Farshid
Mohammadi Sichani, Mehrdad
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
The objective of this study was to evaluate the efficacy of adding single doses of ceftriaxone and amikacin to a ciprofloxacin plus metronidazole regimen on the reduction of infectious complications following transrectal ultrasound-guided prostate biopsy (TRUS Bx).
Materials and Methods.
Four hundred and fifty patients who were candidates for TRUS Bx were divided into two groups of 225 each.
The control group received ciprofloxacin 500 mg orally every 12 hours together with metronidazole 500 mg orally every 8 hours from the day prior to the procedure until the fifth postoperative day.
In the second group, single doses of ceftriaxone 1 g by intravenous infusion and amikacin 5 mg/kg intramuscularly were administered 30–60 minutes before TRUS Bx in addition to the oral antimicrobials described for group 1.
The incidence of infection was compared between the groups.
Results.
The incidence of infectious complications in the intervention group was significantly lower than that in the control group (4.6% versus 0.9%, p=0.017).
Conclusion.
The addition of single doses of intramuscular amikacin and intravenously infused ceftriaxone to our prophylactic regimen of ciprofloxacin plus metronidazole resulted in a statistically significant reduction of infectious complications following TRUS Bx.
American Psychological Association (APA)
Izadpanahi, Mohammad-Hossein& Nouri-Mahdavi, Kia& Majidi, Seyed Mahmood& Khorrami, Mohammad-Hatef& Alizadeh, Farshid& Mohammadi Sichani, Mehrdad. 2017. Addition of Ceftriaxone and Amikacin to a Ciprofloxacin plus Metronidazole Regimen for Preventing Infectious Complications of Transrectal Ultrasound-Guided Prostate Biopsy: A Randomized Controlled Trial. Advances in Urology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1131029
Modern Language Association (MLA)
Izadpanahi, Mohammad-Hossein…[et al.]. Addition of Ceftriaxone and Amikacin to a Ciprofloxacin plus Metronidazole Regimen for Preventing Infectious Complications of Transrectal Ultrasound-Guided Prostate Biopsy: A Randomized Controlled Trial. Advances in Urology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1131029
American Medical Association (AMA)
Izadpanahi, Mohammad-Hossein& Nouri-Mahdavi, Kia& Majidi, Seyed Mahmood& Khorrami, Mohammad-Hatef& Alizadeh, Farshid& Mohammadi Sichani, Mehrdad. Addition of Ceftriaxone and Amikacin to a Ciprofloxacin plus Metronidazole Regimen for Preventing Infectious Complications of Transrectal Ultrasound-Guided Prostate Biopsy: A Randomized Controlled Trial. Advances in Urology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1131029
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131029