Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy
Joint Authors
Sagnelli, Caterina
Sagnelli, Evangelista
Morisco, Filomena
Stroffolini, Tommaso
Babudieri, Sergio
Furlan, Caterina
Pirisi, Mario
Russello, Maurizio
Smedile, Antonina
Almasio, Piero Luigi
Pisaturo, Mariantonietta
Source
Canadian Journal of Gastroenterology and Hepatology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
To evaluate the characteristics of alcohol-related chronic liver disease (CLD) in Italy and their potential changes over time.
Patients and Methods.
Subjects with CLD were enrolled in two national surveys performed in 2001 and in 2014 in Italy.
The two surveys prospectively recruited patients aged ≥ 18 years referring to more than 80 Italian liver units scattered all over the country using similar clinical approach, analytical methods, and threshold of risky alcohol intake definition (≥ 3 units/day in men and ≥ 2 units/day in women).
Results.
Out of 12,256 enrolled subjects, 2,717 (22.2%) reported a risky alcohol intake.
Of them, anti-HCV positive was observed in 48.3% of subjects.
The overall sex ratio (M/F) was 3.1, decreasing from 3.8 in 2001 to 1.3 in 2014.
Women were significantly older than men (58.9 versus 53.1 years; p < 0.01 ) and an increasing ageing over time was observed in both sexes.
The proportion of subjects with liver cirrhosis increased over time in both sexes, and decompensated stage (Child B or C) was detected in 55.9% of cases in 2001 and 46.0% in 2014.
Conclusions.
Risky alcohol intake plays a role in more than one-fifth of CLD in Italy, with a shift over time towards an older age and a more severe liver disease stage.
These data put alcohol back in the spotlight with an important role in CLD in the years to come in Italy.
American Psychological Association (APA)
Stroffolini, Tommaso& Sagnelli, Evangelista& Sagnelli, Caterina& Morisco, Filomena& Babudieri, Sergio& Furlan, Caterina…[et al.]. 2018. Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy. Canadian Journal of Gastroenterology and Hepatology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131075
Modern Language Association (MLA)
Stroffolini, Tommaso…[et al.]. Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy. Canadian Journal of Gastroenterology and Hepatology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1131075
American Medical Association (AMA)
Stroffolini, Tommaso& Sagnelli, Evangelista& Sagnelli, Caterina& Morisco, Filomena& Babudieri, Sergio& Furlan, Caterina…[et al.]. Characteristics and Changes over Time of Alcohol-Related Chronic Liver Diseases in Italy. Canadian Journal of Gastroenterology and Hepatology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131075
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131075