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De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses
Joint Authors
Yang, Chi
Xiao, Donglai
Ma, Lu
Ying, Zhenghe
Jiang, Xiaoling
Lin, Yan-quan
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-25
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Known to be rich in β-glucan, Sparassis latifolia (S.
latifolia) is a valuable edible fungus cultivated in East Asia.
A few studies have suggested that S.
latifolia is effective on antidiabetic, antihypertension, antitumor, and antiallergen medications.
However, it is still unclear genetically why the fungus has these medical effects, which has become a key bottleneck for its further applications.
To provide a better understanding of this fungus, we sequenced its whole genome, which has a total size of 48.13 megabases (Mb) and contains 12,471 predicted gene models.
We then performed comparative and phylogenetic analyses, which indicate that S.
latifolia is closely related to a few species in the antrodia clade including Fomitopsis pinicola, Wolfiporia cocos, Postia placenta, and Antrodia sinuosa.
Finally, we annotated the predicted genes.
Interestingly, the S.
latifolia genome encodes most enzymes involved in carbohydrate and glycoconjugate metabolism and is also enriched in genes encoding enzymes critical to secondary metabolite biosynthesis and involved in indole, terpene, and type I polyketide pathways.
As a conclusion, the genome content of S.
latifolia sheds light on its genetic basis of the reported medicinal properties and could also be used as a reference genome for comparative studies on fungi.
American Psychological Association (APA)
Xiao, Donglai& Ma, Lu& Yang, Chi& Ying, Zhenghe& Jiang, Xiaoling& Lin, Yan-quan. 2018. De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1131129
Modern Language Association (MLA)
Xiao, Donglai…[et al.]. De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1131129
American Medical Association (AMA)
Xiao, Donglai& Ma, Lu& Yang, Chi& Ying, Zhenghe& Jiang, Xiaoling& Lin, Yan-quan. De Novo Sequencing of a Sparassis latifolia Genome and Its Associated Comparative Analyses. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1131129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131129