Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana
Joint Authors
Ephraim, Richard K. D.
Sakyi, Samuel A.
Danquah, Kwabena O.
Fondjo, Linda Ahenkorah
Enimil, Anthony
Frimpong, Venus
Darkoh, Esther Love
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tuberculosis (TB) is a major cause of human mortality particularly in association with the human immunodeficiency virus (HIV).
Nocardia spp.
has emerged as an opportunistic infection especially in HIV patients.
The high prevalence of TB and HIV coupled with the lack of a definitive laboratory diagnosis for Nocardia spp.
could lead to misdiagnosed pulmonary TB.
This study determined the prevalence of pulmonary infections due to Nocardia spp.
and Mycobacterium tuberculosis in sputum of HIV and non-HIV patients with suspected pulmonary tuberculosis at KATH.
A total of sixty sputum samples were obtained from HIV and non-HIV patients with suspected pulmonary tuberculosis.
Samples were examined by fluorescence based Ziehl–Neelsen staining, culture, and PCR methods.
The prevalence of Nocardia spp.
and Mycobacterium tuberculosis was 18.3% and 20%, respectively, with the latter having the highest rate among patients aged 21–40 years (P=0.075).
The prevalence of Nocardia spp.
among HIV patients was 90.9% whilst 16.7% of the patients had HIV/Nocardia spp.
coinfection.
Detection of Mycobacterium tuberculosis by fluorescence-based Ziehl–Neelsen staining, culture, and PCR yielded 9 (15%), 11 (18.3%), and 12 (20%), respectively.
There is a high prevalence of nocardiosis especially in HIV patients.
PCR is a better diagnostic method that detects both Nocardia spp.
and Mycobacterium tuberculosis and should be incorporated into routine diagnosis for pulmonary infections.
American Psychological Association (APA)
Sakyi, Samuel A.& Danquah, Kwabena O.& Ephraim, Richard K. D.& Enimil, Anthony& Frimpong, Venus& Fondjo, Linda Ahenkorah…[et al.]. 2018. Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131146
Modern Language Association (MLA)
Sakyi, Samuel A.…[et al.]. Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1131146
American Medical Association (AMA)
Sakyi, Samuel A.& Danquah, Kwabena O.& Ephraim, Richard K. D.& Enimil, Anthony& Frimpong, Venus& Fondjo, Linda Ahenkorah…[et al.]. Evaluating the Contribution of Nocardia spp. and Mycobacterium tuberculosis to Pulmonary Infections among HIV and Non-HIV Patients at the Komfo Anokye Teaching Hospital, Ghana. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131146
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131146