A Review on Platelet Activating Factor Inhibitors: Could a New Class of Potent Metal-Based Anti-Inflammatory Drugs Induce Anticancer Properties?
Joint Authors
Papakonstantinou, Vasiliki D.
Lagopati, Nefeli
Tsilibary, Effie C.
Philippopoulos, Athanassios I.
Demopoulos, Constantinos A.
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-28
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
In this minireview, we refer to recent results as far as the Platelet Activating Factor (PAF) inhibitors are concerned.
At first, results of organic compounds (natural and synthetic ones and specific and nonspecific) as inhibitors of PAF are reported.
Emphasis is given on recent results about a new class of the so-called metal-based inhibitors of PAF.
A small library of 30 metal complexes has been thus created; their anti-inflammatory activity has been further evaluated owing to their inhibitory effect against PAF in washed rabbit platelets (WRPs).
In addition, emphasis has also been placed on the identification of preliminary structure-activity relationships for the different classes of metal-based inhibitors.
American Psychological Association (APA)
Papakonstantinou, Vasiliki D.& Lagopati, Nefeli& Tsilibary, Effie C.& Demopoulos, Constantinos A.& Philippopoulos, Athanassios I.. 2017. A Review on Platelet Activating Factor Inhibitors: Could a New Class of Potent Metal-Based Anti-Inflammatory Drugs Induce Anticancer Properties?. Bioinorganic Chemistry and Applications،Vol. 2017, no. 2017, pp.1-19.
https://search.emarefa.net/detail/BIM-1131161
Modern Language Association (MLA)
Papakonstantinou, Vasiliki D.…[et al.]. A Review on Platelet Activating Factor Inhibitors: Could a New Class of Potent Metal-Based Anti-Inflammatory Drugs Induce Anticancer Properties?. Bioinorganic Chemistry and Applications No. 2017 (2017), pp.1-19.
https://search.emarefa.net/detail/BIM-1131161
American Medical Association (AMA)
Papakonstantinou, Vasiliki D.& Lagopati, Nefeli& Tsilibary, Effie C.& Demopoulos, Constantinos A.& Philippopoulos, Athanassios I.. A Review on Platelet Activating Factor Inhibitors: Could a New Class of Potent Metal-Based Anti-Inflammatory Drugs Induce Anticancer Properties?. Bioinorganic Chemistry and Applications. 2017. Vol. 2017, no. 2017, pp.1-19.
https://search.emarefa.net/detail/BIM-1131161
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131161