Volatile Oils of Nepeta tenuifolia (Jing Jie) as an Alternative Medicine against Multidrug-Resistant Pathogenic Microbes
Joint Authors
Tung, Kwong-Chung
Tseng, Shu-Ying
Liu, Po-Yu
Lee, Yi-Hsuan
Wu, Zong-Yen
Wang, Chao-Min
Cheng, Ching-Chang
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Essential oils from the dried spikes of Nepeta tenuifolia (Benth) are obtained by steam distillation.
Pulegone was identified as the main component in the spikes of N.
tenuifolia through analysis, with greater than 85% purity obtained in this study.
The essential oils are extremely active against all Gram-positive and some Gram-negative reference bacteria, particularly Salmonella enterica, Citrobacter freundii, and Escherichia coli.
The minimum inhibitory concentration was found to be between 0.08 and 0.78% (against S.
enterica), 0.39 and 0.78% (against C.
freundii), and 0.097 and 0.39% (against E.
coli), whereas the minimum bactericidal concentration varied in range from 0.097% to 1.04%.
In general, the essential oils show a strong inhibitory action against all tested reference strains and clinical isolates.
However, the antibacterial activity of EOs against both Pseudomonas aeruginosa reference strains and clinical isolates was relatively lower than other Gram-negative pathogens.
The essential oils of N.
tenuifolia also displayed bactericidal activities (MBC/MIC < 4) in this study.
These findings reflect the bactericidal activity of the essential oils against a wide range of multidrug-resistant clinical pathogens in an in vitro study.
In addition, we propose the fragmentation pathways of pulegone and its derivatives by LC-ESI-MS/MS in this study.
American Psychological Association (APA)
Lee, Yi-Hsuan& Wang, Chao-Min& Liu, Po-Yu& Cheng, Ching-Chang& Wu, Zong-Yen& Tseng, Shu-Ying…[et al.]. 2018. Volatile Oils of Nepeta tenuifolia (Jing Jie) as an Alternative Medicine against Multidrug-Resistant Pathogenic Microbes. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131236
Modern Language Association (MLA)
Lee, Yi-Hsuan…[et al.]. Volatile Oils of Nepeta tenuifolia (Jing Jie) as an Alternative Medicine against Multidrug-Resistant Pathogenic Microbes. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1131236
American Medical Association (AMA)
Lee, Yi-Hsuan& Wang, Chao-Min& Liu, Po-Yu& Cheng, Ching-Chang& Wu, Zong-Yen& Tseng, Shu-Ying…[et al.]. Volatile Oils of Nepeta tenuifolia (Jing Jie) as an Alternative Medicine against Multidrug-Resistant Pathogenic Microbes. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1131236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131236