Identification of Functional Domain(s) of Fibrillarin Interacted with p2 of Rice stripe virus
Joint Authors
Zheng, Luping
He, Jie
Ding, Zuomei
Zhang, Chenlong
Meng, Ruoxue
Source
Canadian Journal of Infectious Diseases and Medical Microbiology
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
p2 of Rice stripe virus may promote virus systemic infection by interacting with the full length of fibrillarin from Nicotiana benthamiana (NbFib2) in the nucleolus and cajal body (CB).
NbFib2 contains three functional domains.
We used yeast two-hybrid, colocalization, and bimolecular fluorescence complementation (BiFC) assays to study the interactions between p2 and the three domains of NbFib2, namely, the N-terminal fragment containing a glycine and arginine-rich (GAR) domain, the central RNA-binding domain, and the C-terminal fragment containing an α-helical domain.
The results show that the N-terminal domain is indispensable for NbFib2 to localize in the nucleolus and cajal body.
p2 binds all three regions of NbFib2, and they target to the nucleus but fail to the nucleolus and cajal bodies (CBs).
American Psychological Association (APA)
Zheng, Luping& He, Jie& Ding, Zuomei& Zhang, Chenlong& Meng, Ruoxue. 2018. Identification of Functional Domain(s) of Fibrillarin Interacted with p2 of Rice stripe virus. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131239
Modern Language Association (MLA)
Zheng, Luping…[et al.]. Identification of Functional Domain(s) of Fibrillarin Interacted with p2 of Rice stripe virus. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1131239
American Medical Association (AMA)
Zheng, Luping& He, Jie& Ding, Zuomei& Zhang, Chenlong& Meng, Ruoxue. Identification of Functional Domain(s) of Fibrillarin Interacted with p2 of Rice stripe virus. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1131239
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131239