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Overview and Critical Appraisal of Arterial Spin Labelling Technique in Brain Perfusion Imaging
Joint Authors
Alsaedi, Amirah
Thomas, David
Bisdas, Sotirios
Golay, Xavier
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-05-08
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Arterial spin labelling (ASL) allows absolute quantification of CBF via a diffusible intrinsic tracer (magnetically labelled blood water) that disperses from the vascular system into neighbouring tissue.
Thus, it can provide absolute CBF quantification, which eliminates the need for the contrast agent, and can be performed repeatedly.
This review will focus on the common ASL acquisition techniques (continuous, pulsed, and pseudocontinuous ASL) and how ASL image quality might be affected by intrinsic factors that may bias the CBF measurements.
We also provide suggestions to mitigate these risks, model appropriately the acquired signal, increase the image quality, and hence estimate the reliability of the CBF, which consists an important noninvasive biomarker.
Emerging methodologies for extraction of new ASL-based biomarkers, such as arterial arrival time (AAT) and arterial blood volume (aBV), will be also briefly discussed.
American Psychological Association (APA)
Alsaedi, Amirah& Thomas, David& Bisdas, Sotirios& Golay, Xavier. 2018. Overview and Critical Appraisal of Arterial Spin Labelling Technique in Brain Perfusion Imaging. Contrast Media & Molecular Imaging،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1131445
Modern Language Association (MLA)
Alsaedi, Amirah…[et al.]. Overview and Critical Appraisal of Arterial Spin Labelling Technique in Brain Perfusion Imaging. Contrast Media & Molecular Imaging No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1131445
American Medical Association (AMA)
Alsaedi, Amirah& Thomas, David& Bisdas, Sotirios& Golay, Xavier. Overview and Critical Appraisal of Arterial Spin Labelling Technique in Brain Perfusion Imaging. Contrast Media & Molecular Imaging. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1131445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131445