Preoperative PETCT 18F-FDG Standardized Uptake by Lymph Nodes as a Significant Prognostic Factor in Patients with Colorectal Cancer
Joint Authors
Chen, Ruohua
Zhou, Xiang
Huang, Gang
Liu, Jianjun
Wang, Yining
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-11-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
We evaluated the prognostic value of preoperative 18F-FDG uptake by suspected lymph nodes (LNs) using 18F-FDG PET/CT in colorectal cancer patients.
Methods.
Patients with CRC underwent 18F-FDG PET/CT before radical surgery.
We used Cox proportional hazards regression to examine the relationship between recurrence and the 18F-FDG maximum standardized uptake value (SUVmax) in the suspected LNs (SUVLN) on 18F-FDG PET/CT.
Results.
Clinical data, treatment modalities, and results from 90 CR C patients were reviewed.
The median follow-up was 19 months (range 3 to 72 months).
Receiver operating characteristic analysis identified SUVLN 1.15 was the optimal cut-off value for predicting recurrence.
SUVLN correlated with tumour size (P=0.045), lymph node metastasis (P=0.03), and recurrence (P<0.0001).
Univariate analysis showed significant associations between recurrence and SUVLN (P=0.017), and tumour grade (P=0.013).
Multivariate analysis identified SUVLN (P<0.0001), and tumour grade (P=0.005) as independent risk factors for recurrence.
Patients with SUVLN ≤ 1.15 and SUVLN > 0.15 differed significantly in terms of recurrence (P<0.0001).
Conclusion.
Preoperative SUVLN measured by 18F-FDG PET/CT was significantly associated with recurrence and had significant prognostic value for recurrence-free survival in patients with colorectal cancer.
American Psychological Association (APA)
Chen, Ruohua& Wang, Yining& Zhou, Xiang& Huang, Gang& Liu, Jianjun. 2018. Preoperative PETCT 18F-FDG Standardized Uptake by Lymph Nodes as a Significant Prognostic Factor in Patients with Colorectal Cancer. Contrast Media & Molecular Imaging،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131461
Modern Language Association (MLA)
Chen, Ruohua…[et al.]. Preoperative PETCT 18F-FDG Standardized Uptake by Lymph Nodes as a Significant Prognostic Factor in Patients with Colorectal Cancer. Contrast Media & Molecular Imaging No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1131461
American Medical Association (AMA)
Chen, Ruohua& Wang, Yining& Zhou, Xiang& Huang, Gang& Liu, Jianjun. Preoperative PETCT 18F-FDG Standardized Uptake by Lymph Nodes as a Significant Prognostic Factor in Patients with Colorectal Cancer. Contrast Media & Molecular Imaging. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131461
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131461