Evans Blue Dye: A Revisit of Its Applications in Biomedicine
Joint Authors
Ni, Y.
Xue, Xing
Yao, Linpeng
Chen, Feng
Yu, Peipei
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Evans blue (EB) dye has owned a long history as a biological dye and diagnostic agent since its first staining application by Herbert McLean Evans in 1914.
Due to its high water solubility and slow excretion, as well as its tight binding to serum albumin, EB has been widely used in biomedicine, including its use in estimating blood volume and vascular permeability, detecting lymph nodes, and localizing the tumor lesions.
Recently, a series of EB derivatives have been labeled with PET isotopes and can be used as theranostics with a broad potential due to their improved half-life in the blood and reduced release.
Some of EB derivatives have even been used in translational applications in clinics.
In addition, a novel necrosis-avid feature of EB has recently been reported in some preclinical animal studies.
Given all these interesting and important advances in EB study, a comprehensive revisiting of EB has been made in its biomedical applications in the review.
American Psychological Association (APA)
Yao, Linpeng& Xue, Xing& Yu, Peipei& Ni, Y.& Chen, Feng. 2018. Evans Blue Dye: A Revisit of Its Applications in Biomedicine. Contrast Media & Molecular Imaging،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1131531
Modern Language Association (MLA)
Yao, Linpeng…[et al.]. Evans Blue Dye: A Revisit of Its Applications in Biomedicine. Contrast Media & Molecular Imaging No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1131531
American Medical Association (AMA)
Yao, Linpeng& Xue, Xing& Yu, Peipei& Ni, Y.& Chen, Feng. Evans Blue Dye: A Revisit of Its Applications in Biomedicine. Contrast Media & Molecular Imaging. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1131531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131531