Herbal Active Ingredients: An Emerging Potential for the Prevention and Treatment of Papillary Thyroid Carcinoma
Joint Authors
Yang, Yang
Chen, Qin
Yu, Wen-Ying
Zhang, Huan-Huan
Zhong, Yu-Sen
Zhang, Song-Zhao
Wang, Jia-Feng
Yu, Chen-Huan
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Papillary thyroid carcinoma (PTC) is the most common subtype of differentiated thyroid cancers in Asian coastal cities, where the patients have increased risk of potentially high or excessive iodine intake.
Given the high metastasis and recurrence of patients with BRAFV600E mutation, the mortality rate of thyroid cancer has recently shown an upward trend.
A variety of therapies, including surgery, radiotherapy, and chemotherapy, have been used to treat thyroid cancer, but these therapies still have limitations, including postoperative complications, drug resistance, poor efficacy, or serious side effects.
Recent studies have shown the potential of active ingredients derived from herbal medicine in inhibiting PTC via various cell signaling pathways.
Some plant-derived compounds, such as apigenin, genistein, and curcumin, are also known to prevent and treat PTC.
This article summarizes the recent advances in the structure-functional impact of anti-PTC active ingredients and their effects on PTC cells and tumor microenvironments with an emphasis on their challenges from basic research to clinical practice.
American Psychological Association (APA)
Yang, Yang& Chen, Qin& Yu, Wen-Ying& Zhang, Huan-Huan& Zhong, Yu-Sen& Zhang, Song-Zhao…[et al.]. 2020. Herbal Active Ingredients: An Emerging Potential for the Prevention and Treatment of Papillary Thyroid Carcinoma. BioMed Research International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1131567
Modern Language Association (MLA)
Yang, Yang…[et al.]. Herbal Active Ingredients: An Emerging Potential for the Prevention and Treatment of Papillary Thyroid Carcinoma. BioMed Research International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1131567
American Medical Association (AMA)
Yang, Yang& Chen, Qin& Yu, Wen-Ying& Zhang, Huan-Huan& Zhong, Yu-Sen& Zhang, Song-Zhao…[et al.]. Herbal Active Ingredients: An Emerging Potential for the Prevention and Treatment of Papillary Thyroid Carcinoma. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1131567
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131567