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Functional Parameters of 18F-FDG PETCT in Patients with Primary Testicular Diffuse Large B-Cell Lymphoma
Joint Authors
Zhu, Sha
Ma, Xuelei
Pang, Fuwen
Yang, Jing
Xu, Miao
Dong, Yiting
Hao, Jianqi
Source
Contrast Media & Molecular Imaging
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Fluorine-18 fluorodeoxyglucose (18F-FDG) positron-emission tomography/computed tomography (PET/CT), a hybrid imaging technique that simultaneously provides functional and anatomical information, has been reported to be useful in lymphoma.
The present study was to evaluate the functional parameters of 18F-FDG PET/CT in patients with testicular diffuse large B-cell lymphoma (DLBCL).
We retrospectively reviewed medical records of 5095 patients with lymphoma who treated at West China Hospital between March 2003 and January 2017, and selected patients with 18F-FDG PET/CT findings and subsequently biopsy confirmed the invasion of testis with DLBCL.
Maximum standardized uptake values (SUVmax), peak standardized uptake values (SUVpeak), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) of the patients were measured.
We evaluated the characteristics of 18F-FDG PET/CT in this population.
Six patients ranged in age from 37 to 73 years (median age, 58 years) were included in the analysis.
The mean SUVmax was 11.09 and varied between 7.20 and 19.75; mean SUVpeak was 9.56 and ranged between 6.79 and 14.39.
In addition, mean MTV 42% was 18.4 and varied between 1.3 and 61.6; mean MTV 2.5 was 34.7 and varied significantly between 1.6 and 141.9.
With regard to TLG, mean TLG 42% was 168.906 and ranged from 7.514 to 687.004, while mean TLG 2.5 was 253.972 and ranged from 8.400 to 1127.802.
In conclusion, 18F-FDG PET/CT scan is a useful tool in patients with testicular DLBCL.
SUV, MTV, and TLG may vary a lot in different patients.
SUVmax of testicular DLBCL lesion is relatively higher than that of normal testis.
Also, we provided a set of MTV and TLG data and firstly showed their significant correlation with overall survival, which indicated a potential prognostic value of MTV and TLG.
However, studies with larger population are needed to confirm these findings.
American Psychological Association (APA)
Yang, Jing& Zhu, Sha& Pang, Fuwen& Xu, Miao& Dong, Yiting& Hao, Jianqi…[et al.]. 2018. Functional Parameters of 18F-FDG PETCT in Patients with Primary Testicular Diffuse Large B-Cell Lymphoma. Contrast Media & Molecular Imaging،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131595
Modern Language Association (MLA)
Yang, Jing…[et al.]. Functional Parameters of 18F-FDG PETCT in Patients with Primary Testicular Diffuse Large B-Cell Lymphoma. Contrast Media & Molecular Imaging No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1131595
American Medical Association (AMA)
Yang, Jing& Zhu, Sha& Pang, Fuwen& Xu, Miao& Dong, Yiting& Hao, Jianqi…[et al.]. Functional Parameters of 18F-FDG PETCT in Patients with Primary Testicular Diffuse Large B-Cell Lymphoma. Contrast Media & Molecular Imaging. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1131595
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131595