Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia
Joint Authors
Zhou, Yaguang
Yu, Shui
Zhao, Jimin
Feng, Xinyue
Zhang, Meinan
Zhao, Zigang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-08-04
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Androgenetic alopecia (AGA) represents the most frequent clinical complaint encountered by dermatologists and is characterized by a progressive miniaturization of the hair follicle.
However, the efficacy and safety of current medical treatment remain limited, and more personalized therapeutic approaches for AGA are needed.
Therefore, the present study is aimed at investigating the efficacy and safety of botulinum toxin type A (BTA) in patients with AGA.
Methods.
63 patients with AGA meeting the inclusion criteria were included in this study and treated with BTA injection or BTA injection combined with oral finasteride (FNS).
In the scalp, 30 sites were injected with 100 U of BTA in each site and patients received BTA after every 3 months for a total of 4 times.
Hair counts, head photographs, evaluation scores, and self-assessment were assessed in patients with AGA.
Results.
Hair counts in both groups at all time points were significantly higher as compared with those before treatment.
After 4 times of treatment, hair counts in the BTA+FNS group were higher than those in the BTA group.
Hair growth and density were significantly augmented, and the area of hair loss was attenuated after each treatment as revealed by head photographs.
The effective rates of BTA and BTA+FNS groups were 73.3% and 84.8%, respectively, following 4 times treatment.
Conclusion.
BTA is a safe and effective therapeutic strategy for the treatment of AGA without adverse effects, and BTA combined with FNS exhibited a superior therapeutic effect than BTA alone.
American Psychological Association (APA)
Zhou, Yaguang& Yu, Shui& Zhao, Jimin& Feng, Xinyue& Zhang, Meinan& Zhao, Zigang. 2020. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1131693
Modern Language Association (MLA)
Zhou, Yaguang…[et al.]. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1131693
American Medical Association (AMA)
Zhou, Yaguang& Yu, Shui& Zhao, Jimin& Feng, Xinyue& Zhang, Meinan& Zhao, Zigang. Effectiveness and Safety of Botulinum Toxin Type A in the Treatment of Androgenetic Alopecia. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1131693
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131693