Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases

Joint Authors

de Melo Silva, Jean
Pinheiro-Silva, Renato
Dhyani, Anamika
Pontes, Gemilson Soares

Source

BioMed Research International

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-10-26

Country of Publication

Egypt

No. of Pages

14

Main Subjects

Medicine

Abstract EN

Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are widely distributed throughout the world.

EBV is linked to various hematological and autoimmune disorders whereas CMV might play important role in the progression of chronic hematological diseases, such as hemoglobinopathies, lymphomas, myelomas, hemophilia, and aplastic and sickle cell anemia.

Both viruses produce a viral homolog of human interleukin-10 that can cause general suppression of immune response, increasing susceptibility to other infections.

These viruses can remain latent in the host cells and be reactivated when the host immune system is compromised.

Studies showing the impact of CMV and EBV infections on hematological disorders are scarce and unclear in the context of coinfection.

This review intends to present the biology, prevalence, and impact of CMV and EBV infections in patients with hematological diseases.

American Psychological Association (APA)

de Melo Silva, Jean& Pinheiro-Silva, Renato& Dhyani, Anamika& Pontes, Gemilson Soares. 2020. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1131769

Modern Language Association (MLA)

de Melo Silva, Jean…[et al.]. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1131769

American Medical Association (AMA)

de Melo Silva, Jean& Pinheiro-Silva, Renato& Dhyani, Anamika& Pontes, Gemilson Soares. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1131769

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1131769