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Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases
Joint Authors
de Melo Silva, Jean
Pinheiro-Silva, Renato
Dhyani, Anamika
Pontes, Gemilson Soares
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infections are widely distributed throughout the world.
EBV is linked to various hematological and autoimmune disorders whereas CMV might play important role in the progression of chronic hematological diseases, such as hemoglobinopathies, lymphomas, myelomas, hemophilia, and aplastic and sickle cell anemia.
Both viruses produce a viral homolog of human interleukin-10 that can cause general suppression of immune response, increasing susceptibility to other infections.
These viruses can remain latent in the host cells and be reactivated when the host immune system is compromised.
Studies showing the impact of CMV and EBV infections on hematological disorders are scarce and unclear in the context of coinfection.
This review intends to present the biology, prevalence, and impact of CMV and EBV infections in patients with hematological diseases.
American Psychological Association (APA)
de Melo Silva, Jean& Pinheiro-Silva, Renato& Dhyani, Anamika& Pontes, Gemilson Soares. 2020. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1131769
Modern Language Association (MLA)
de Melo Silva, Jean…[et al.]. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1131769
American Medical Association (AMA)
de Melo Silva, Jean& Pinheiro-Silva, Renato& Dhyani, Anamika& Pontes, Gemilson Soares. Cytomegalovirus and Epstein-Barr Infections: Prevalence and Impact on Patients with Hematological Diseases. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1131769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131769