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Comparative Screening Analytic Methods for Elderly of Blood Methylmercury Concentration between Two Analytical Institutions
Joint Authors
Kim, Byoung-Gwon
Hong, Young-Seoub
Haraguchi, Koichi
Sakomoto, Mineshi
Lim, Hyoun-Ju
Seo, Jeong-Wook
Kim, Yu-Mi
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Methylmercury is widely known to be a toxic substance in the human, especially a nervous system.
However, it is difficult to accurately measure the amount of methylmercury in blood, and the form of methylmercury is variously presented.
The purpose of study was to compare the total mercury and methylmercury measurements techniques and detection levels between analytical institutions in two countries using the same elderly human blood samples.
Total mercury using gold amalgamation direct mercury analysis method (both) and methylmercury using the dithizone extraction and gas chromatography-electron capture detector (GC-ECD) method (N Lab in Japan) and the cold vapor atomic fluorescence spectrophotometer (CVAFS) method (D Lab in Korea) were measured in 47 subjects who agreed to participate in this study.
Total mercury concentrations in both analytical laboratories were observed at similar levels (9.4 versus 9.5 ug/kg, p=0.898) and the distribution was highly correlated.
However, the concentration of methylmercury showed some difference between two laboratories (9.1 versus 8.6 ug/kg, p<0.001).
Due to different recovery rates by different analytical methods, it is assumed that the methyl/total mercury ratio in N lab in Japan was higher than D lab in Korea (96.8 versus 90.4%, p<0.001).
The GC-ECD was more sensitive method than CVAFS in methylmercury analytic techniques.
American Psychological Association (APA)
Kim, Byoung-Gwon& Hong, Young-Seoub& Haraguchi, Koichi& Sakomoto, Mineshi& Lim, Hyoun-Ju& Seo, Jeong-Wook…[et al.]. 2018. Comparative Screening Analytic Methods for Elderly of Blood Methylmercury Concentration between Two Analytical Institutions. Computational and Mathematical Methods in Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1131845
Modern Language Association (MLA)
Kim, Byoung-Gwon…[et al.]. Comparative Screening Analytic Methods for Elderly of Blood Methylmercury Concentration between Two Analytical Institutions. Computational and Mathematical Methods in Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1131845
American Medical Association (AMA)
Kim, Byoung-Gwon& Hong, Young-Seoub& Haraguchi, Koichi& Sakomoto, Mineshi& Lim, Hyoun-Ju& Seo, Jeong-Wook…[et al.]. Comparative Screening Analytic Methods for Elderly of Blood Methylmercury Concentration between Two Analytical Institutions. Computational and Mathematical Methods in Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1131845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1131845