Evaluation of Xpert MTBRIF for the Diagnosis of Lymphatic Tuberculosis
Joint Authors
Li, Hou-He
He, Zhi-Jian
Liang, Jia-Qi
Li, Gui-Lin
Xie, Tian-Ao
Liu, Ye-Ling
Li, Zhong-Wei
Feng, Xuan-Cheng
Xia, Yong
Guo, Xu-Guang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
The World Health Organization approved the use of Xpert MTB/RIF for the detection of Mycobacterium tuberculosis DNA, which has significantly improved the diagnosis of tuberculosis.
In this study, our main objective was to evaluate the diagnostic efficacy of Xpert MTB/RIF for lymphoid tuberculosis to determine whether Xpert MTB/RIF could be used as a routine detection method.
Materials and Methods.
We searched four databases for the relevant literature published from May 2007 to December 2019.
The quality of the literature was evaluated with reference to the evaluation criteria.
Data that were extracted from the literature on Xpert MTB/RIF diagnosis of lymphatic tuberculosis were used to plot the summary receiver operating characteristic (SROC) curve, after which the software was used to combine and analyze the accuracy of these data.
Results.
A total of 27 studies were included.
The sensitivity of Xpert MTB/RIF for detecting lymphatic tuberculosis was 0.79 (95% CI (0.77, 0.81)), the specificity was 0.88 (95% CI (0.87, 0.90)), and the positive likelihood ratio (PLR) was 7.21 (95% CI (4.93, 10.55)).
In addition, the negative likelihood ratio (NLR) was 0.25 (95% CI (0.19, 0.32)) and the diagnostic odds ratio (DOR) was 40.23 (95% CI (24.53, 65.98)).
At the same time, we used the extracted data to make the SROC curve, obtaining the following parameters: area under the curve AUC=0.9144, Q=0.8470 (SE=0.0163).
Conclusion.
Xpert MTB/RIF has high accuracy in detecting lymphatic tuberculosis, and it can be used to quickly and easily diagnose lymphatic tuberculosis at an early stage as a general method.
American Psychological Association (APA)
Li, Gui-Lin& Xie, Tian-Ao& Liu, Ye-Ling& Li, Zhong-Wei& Feng, Xuan-Cheng& Xia, Yong…[et al.]. 2020. Evaluation of Xpert MTBRIF for the Diagnosis of Lymphatic Tuberculosis. BioMed Research International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1132198
Modern Language Association (MLA)
Li, Gui-Lin…[et al.]. Evaluation of Xpert MTBRIF for the Diagnosis of Lymphatic Tuberculosis. BioMed Research International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1132198
American Medical Association (AMA)
Li, Gui-Lin& Xie, Tian-Ao& Liu, Ye-Ling& Li, Zhong-Wei& Feng, Xuan-Cheng& Xia, Yong…[et al.]. Evaluation of Xpert MTBRIF for the Diagnosis of Lymphatic Tuberculosis. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1132198
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1132198