Quinonoids: Therapeutic Potential for Lung Cancer Treatment
Joint Authors
Yu, Wen-Ying
Zhang, Huan-Huan
Yu, Chen-Huan
Ying, Hua-Zhong
Chen, Hao-Kun
Fang, Jie
Wu, Fang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-07
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Lung cancer is the leading cause of cancer-related deaths worldwide.
Owing to its high incidence and mortality, the development and discovery of novel anticancer drugs is of great importance.
In recent years, many breakthroughs have been achieved in the search for effective anticancer substances from natural products.
Many anticancer drugs used clinically and proven to be effective are derived from natural products.
Quinonoids, including naphthoquinones, phenanthrenequinones, benzoquinones, and anthraquinones, constitute a large group of natural bioactive compounds that widely exist in higher and lower plant species.
Given that most of these compounds possess anticancer effects, they are applied in many cancer studies, especially in lung cancer research.
They can promote apoptosis, induce autophagy, and inhibit proliferation, angiogenesis, and cell invasion and migration.
Some drugs can enhance anticancer effects when combined with other drugs.
Thus, quinonoids have broad application prospects in the treatment of lung cancer.
Here, we summarize the previous studies on the antilung cancer activities of quinonoids together with their underlying mechanisms and analyze the common research targets with different effects so as to provide references for the discovery of quinonoids against lung cancer.
American Psychological Association (APA)
Ying, Hua-Zhong& Yu, Chen-Huan& Chen, Hao-Kun& Zhang, Huan-Huan& Fang, Jie& Wu, Fang…[et al.]. 2020. Quinonoids: Therapeutic Potential for Lung Cancer Treatment. BioMed Research International،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1132514
Modern Language Association (MLA)
Ying, Hua-Zhong…[et al.]. Quinonoids: Therapeutic Potential for Lung Cancer Treatment. BioMed Research International No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1132514
American Medical Association (AMA)
Ying, Hua-Zhong& Yu, Chen-Huan& Chen, Hao-Kun& Zhang, Huan-Huan& Fang, Jie& Wu, Fang…[et al.]. Quinonoids: Therapeutic Potential for Lung Cancer Treatment. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1132514
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1132514