Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors
Joint Authors
Liao, Guolin
Ruan, Huaqiang
Peng, Peng
Liu, Shiquan
Qin, Jianfu
Liang, Zhihai
Tang, Guodu
Qin, Mengbin
Huang, Jie’an
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
Many epidemiological studies have investigated the risk factors for clonorchiasis, but endoscopic findings of this disease in endoscopic retrograde cholangiopancreatography (ERCP) have not been well characterized.
In this study, we evaluated clonorchiasis in ERCP in patients with biliary and pancreatic diseases.
Methods.
This was a retrospective two-center study in hospitalized patients who received ERCP between January 2012 and October 2018.
All patients were divided into clonorchiasis and nonclonorchiasis groups.
Data were analyzed using univariate analysis and multivariate analyses.
Results.
A total of 1119 patients were included, and clonorchiasis was diagnosed in 19.2% patients.
Detection of Clonorchis sinensis eggs in bile samples was higher than that in fecal samples (85.9% vs.
58.7%; P=0.001).
In multivariate analysis, male patients (95% confidence interval (CI): 1.945–4.249, P=0.0001), age≤60 years old (95% CI: 1.212–2.474, P=0.003), patients with papilla fistula (95% CI: 0.081–0.900, P=0.033), and patients with a common bile duct (CBD) diameter<12 mm (95% CI: 1.093–2.130, P=0.013) were associated with clonorchiasis incidence.
Nonclonorchiasis endoscopic diagnosis did not significantly correlate with clonorchiasis incidence (P>0.05).
Conclusions.
The detection of C.
sinensis eggs was significantly higher in bile than in fecal samples; thus, bile samples represent a preferable sample for the diagnosis of clonorchiasis in patients with biliary obstruction.
We found that male, age≤60 years old, and CBD diameter<12 mm were independent risk factors for clonorchiasis, while papilla fistula was a protective factor.
American Psychological Association (APA)
Liao, Guolin& Ruan, Huaqiang& Peng, Peng& Liu, Shiquan& Qin, Jianfu& Liang, Zhihai…[et al.]. 2020. Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132844
Modern Language Association (MLA)
Liao, Guolin…[et al.]. Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1132844
American Medical Association (AMA)
Liao, Guolin& Ruan, Huaqiang& Peng, Peng& Liu, Shiquan& Qin, Jianfu& Liang, Zhihai…[et al.]. Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1132844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1132844