Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag
Joint Authors
Saotome, Masao
Satoh, Terumori
Suwa, Kenichiro
Ohtani, Hayato
Nagata, Yasuyuki
Ono, Takaaki
Maekawa, Yuichiro
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Eltrombopag, a nonpeptide thrombopoietin receptor agonist (TPO-RA), has been reported to be an effective therapy for chronic immune thrombocytopenia (ITP).
However, a higher incidence of arterial and venous thromboembolic events was reported after using eltrombopag.
Case Presentation.
A 67-year-old man, treated with eltrombopag due to chronic ITP, was admitted due to acute coronary syndrome (ACS).
Although coronary angiography revealed no occlusion, cardiac magnetic resonance imaging suggested a myocardial infarction in the territory of the left circumflex coronary artery.
Three months after the ACS event, the obtuse marginal branches exhibited significant stenosis; hence, a percutaneous coronary intervention (PCI) was performed to implant a zotarolimus-eluting stent under the treatment of a dual antiplatelet therapy.
However, stent thrombosis occurred 3 hours after PCI and required three other PCIs during the eltrombopag treatment.
Conclusion.
We present a case of an ITP patient, who experienced repeated coronary and stent thrombosis during the treatment with eltrombopag.
We propose that the risk of ACS and consequent coronary stent thrombosis should be considered before the introduction of eltrombopag.
American Psychological Association (APA)
Satoh, Terumori& Saotome, Masao& Suwa, Kenichiro& Ohtani, Hayato& Nagata, Yasuyuki& Ono, Takaaki…[et al.]. 2019. Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag. Case Reports in Cardiology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1133622
Modern Language Association (MLA)
Satoh, Terumori…[et al.]. Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag. Case Reports in Cardiology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1133622
American Medical Association (AMA)
Satoh, Terumori& Saotome, Masao& Suwa, Kenichiro& Ohtani, Hayato& Nagata, Yasuyuki& Ono, Takaaki…[et al.]. Recurrent Coronary Thrombus in a Patient with Chronic Immune Thrombocytopenia with Treatment Using Eltrombopag. Case Reports in Cardiology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1133622
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133622