Positive Effect of Higher Adult Body Mass Index on Overall Survival of Digestive System Cancers Except Pancreatic Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Cui, Jianfeng
Han, Jie
Zhou, Yumei
Zheng, Yuxiu
Wang, Miaomiao
Chen, Pengxiang
Yu, Jinming
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-29
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
High body mass index (BMI) has been inconsistently associated with overall survival (OS) of digestive system cancers (DSCs).
This meta-analysis was conducted to investigate whether high BMI was associated with DSCs prognosis.
34 studies were accepted, with a total of 23,946 DSC cases.
Hazard ratios (HRs) with 95% confidence intervals (95% CIs) for OS in BMI categories from individual studies were extracted and pooled by random-effect model.
The overall HR of DSCs except pancreatic cancer for OS of adult overweight cases was 0.76 (95% CI = 0.67–0.85).
DSC individuals except pancreatic cancer with adult obesity were at decreased risk for OS (HR = 0.85, 95% CI = 0.72–0.98).
Among DSC patients except pancreatic cancer, the overall HR for the highest versus the lowest BMI category was 0.82 (95% CI = 0.71–0.92).
Additionally, comparing the highest and lowest BMI categories, the combined HR of pancreatic cancer was 1.22 (95% CI = 1.01–1.43).
Our meta-analysis suggested an increased OS among adult overweight and obese DSC survivors except pancreatic cancer.
Overweight and obesity in adulthood may be important prognostic factors that indicate an increased survival from DSC patients except pancreatic cancer.
American Psychological Association (APA)
Han, Jie& Zhou, Yumei& Zheng, Yuxiu& Wang, Miaomiao& Cui, Jianfeng& Chen, Pengxiang…[et al.]. 2017. Positive Effect of Higher Adult Body Mass Index on Overall Survival of Digestive System Cancers Except Pancreatic Cancer: A Systematic Review and Meta-Analysis. BioMed Research International،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1133624
Modern Language Association (MLA)
Han, Jie…[et al.]. Positive Effect of Higher Adult Body Mass Index on Overall Survival of Digestive System Cancers Except Pancreatic Cancer: A Systematic Review and Meta-Analysis. BioMed Research International No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1133624
American Medical Association (AMA)
Han, Jie& Zhou, Yumei& Zheng, Yuxiu& Wang, Miaomiao& Cui, Jianfeng& Chen, Pengxiang…[et al.]. Positive Effect of Higher Adult Body Mass Index on Overall Survival of Digestive System Cancers Except Pancreatic Cancer: A Systematic Review and Meta-Analysis. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1133624
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133624