Genetic Variation and Its Reflection on Posttranslational Modifications in Frequency Clock and Mating Type a-1 Proteins in Sordaria fimicola
Joint Authors
Mukhtar, Hamid
Arif, Rabia
Akram, Faiza
Jamil, Tazeen
Lee, Siu Fai
Saleem, Muhammad
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Posttranslational modifications (PTMs) occur in all essential proteins taking command of their functions.
There are many domains inside proteins where modifications take place on side-chains of amino acids through various enzymes to generate different species of proteins.
In this manuscript we have, for the first time, predicted posttranslational modifications of frequency clock and mating type a-1 proteins in Sordaria fimicola collected from different sites to see the effect of environment on proteins or various amino acids pickings and their ultimate impact on consensus sequences present in mating type proteins using bioinformatics tools.
Furthermore, we have also measured and walked through genomic DNA of various Sordaria strains to determine genetic diversity by genotyping the short sequence repeats (SSRs) of wild strains of S.
fimicola collected from contrasting environments of two opposing slopes (harsh and xeric south facing slope and mild north facing slope) of Evolution Canyon (EC), Israel.
Based on the whole genome sequence of S.
macrospora, we targeted 20 genomic regions in S.
fimicola which contain short sequence repeats (SSRs).
Our data revealed genetic variations in strains from south facing slope and these findings assist in the hypothesis that genetic variations caused by stressful environments lead to evolution.
American Psychological Association (APA)
Arif, Rabia& Akram, Faiza& Jamil, Tazeen& Mukhtar, Hamid& Lee, Siu Fai& Saleem, Muhammad. 2017. Genetic Variation and Its Reflection on Posttranslational Modifications in Frequency Clock and Mating Type a-1 Proteins in Sordaria fimicola. BioMed Research International،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1133777
Modern Language Association (MLA)
Arif, Rabia…[et al.]. Genetic Variation and Its Reflection on Posttranslational Modifications in Frequency Clock and Mating Type a-1 Proteins in Sordaria fimicola. BioMed Research International No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1133777
American Medical Association (AMA)
Arif, Rabia& Akram, Faiza& Jamil, Tazeen& Mukhtar, Hamid& Lee, Siu Fai& Saleem, Muhammad. Genetic Variation and Its Reflection on Posttranslational Modifications in Frequency Clock and Mating Type a-1 Proteins in Sordaria fimicola. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1133777
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133777