Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?
Joint Authors
Angeletti, Silvia
Pascarella, Stefano
Ciccozzi, Massimo
Bianchi, Martina
Benvenuto, Domenico
Giovanetti, Marta
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The Coronavirus Disease 2019 (COVID-19) is a new viral infection caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2).
Genomic analyses have revealed that SARS-CoV-2 is related to Pangolin and Bat coronaviruses.
In this report, a structural comparison between the Sars-CoV-2 Envelope and Membrane proteins from different human isolates with homologous proteins from closely related viruses is described.
The analyses here reported show the high structural similarity of Envelope and Membrane proteins to the counterparts from Pangolin and Bat coronavirus isolates.
However, the comparisons have also highlighted structural differences specific of Sars-CoV-2 proteins which may be correlated to the cross-species transmission and/or to the properties of the virus.
Structural modelling has been applied to map the variant sites onto the predicted three-dimensional structure of the Envelope and Membrane proteins.
American Psychological Association (APA)
Bianchi, Martina& Benvenuto, Domenico& Giovanetti, Marta& Angeletti, Silvia& Ciccozzi, Massimo& Pascarella, Stefano. 2020. Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1133920
Modern Language Association (MLA)
Bianchi, Martina…[et al.]. Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1133920
American Medical Association (AMA)
Bianchi, Martina& Benvenuto, Domenico& Giovanetti, Marta& Angeletti, Silvia& Ciccozzi, Massimo& Pascarella, Stefano. Sars-CoV-2 Envelope and Membrane Proteins: Structural Differences Linked to Virus Characteristics?. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1133920
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133920
