![](/images/graphics-bg.png)
Novel Treponema pallidum Recombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects
Joint Authors
Deryabin, Dmitry
Kubanov, Aleksey
Runina, Anastassia
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-24
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The recombinant protein technology considerably promoted the development of rapid and accurate treponema-specific laboratory diagnostics of syphilis infection.
For the last ten years, the immunodominant recombinant inner membrane lipoproteins are proved to be sensitive and specific antigens for syphilis screening.
However, the development of an enlarged T.
pallidum antigen panel for diagnostics of early and late syphilis and differentiation of syphilis stages or cured syphilis remains as actual goal of multidisciplinary expertise.
Current review revealed novel recombinant antigens: surface-exposed proteins, adhesins, and periplasmic and flagellar proteins, which are promising candidates for the improved syphilis serological diagnostics.
The opportunities and limitations of diagnostic usage of these antigens are discussed and the criteria for selection of optimal antigens panel summarized.
American Psychological Association (APA)
Kubanov, Aleksey& Runina, Anastassia& Deryabin, Dmitry. 2017. Novel Treponema pallidum Recombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects. BioMed Research International،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1133925
Modern Language Association (MLA)
Kubanov, Aleksey…[et al.]. Novel Treponema pallidum Recombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects. BioMed Research International No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1133925
American Medical Association (AMA)
Kubanov, Aleksey& Runina, Anastassia& Deryabin, Dmitry. Novel Treponema pallidum Recombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1133925
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133925