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Comparative Analysis of Local Control Prediction Using Different Biophysical Models for Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy
Joint Authors
Huang, Bao-Tian
Zhang, Wu-Zhe
Wu, Li-Li
Lin, Pei-Xian
Lu, Jia-Yang
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
The consistency for predicting local control (LC) data using biophysical models for stereotactic body radiotherapy (SBRT) treatment of lung cancer is unclear.
This study aims to compare the results calculated from different models using the treatment planning data.
Materials and Methods.
Treatment plans were designed for 17 patients diagnosed with primary non-small cell lung cancer (NSCLC) using 5 different fraction schemes.
The Martel model, Ohri model, and the Tai model were used to predict the 2-year LC value.
The Gucken model, Santiago model, and the Tai model were employed to estimate the 3-year LC data.
Results.
We found that the employed models resulted in completely different LC prediction except for the Gucken and the Santiago models which exhibited quite similar 3-year LC data.
The predicted 2-year and 3-year LC values in different models were not only associated with the dose normalization but also associated with the employed fraction schemes.
The greatest difference predicted by different models was up to 15.0%.
Conclusions.
Our results show that different biophysical models influence the LC prediction and the difference is not only correlated to the dose normalization but also correlated to the employed fraction schemes.
American Psychological Association (APA)
Huang, Bao-Tian& Zhang, Wu-Zhe& Wu, Li-Li& Lin, Pei-Xian& Lu, Jia-Yang. 2017. Comparative Analysis of Local Control Prediction Using Different Biophysical Models for Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1133927
Modern Language Association (MLA)
Huang, Bao-Tian…[et al.]. Comparative Analysis of Local Control Prediction Using Different Biophysical Models for Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1133927
American Medical Association (AMA)
Huang, Bao-Tian& Zhang, Wu-Zhe& Wu, Li-Li& Lin, Pei-Xian& Lu, Jia-Yang. Comparative Analysis of Local Control Prediction Using Different Biophysical Models for Non-Small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1133927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133927