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Are the Pathological Characteristics of Prostate Cancer More Aggressive or More Indolent Depending upon the Patient Age?
Joint Authors
He, Zhisong
He, Qun
Zhou, Liqun
Hao, Han
Huang, Cong
Song, Gang
Wang, He
Ji, Guangjie
Cai, Lin
Fang, Dong
Xiong, Gengyan
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-07
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To identify pathological characteristics of prostate cancer according to patient age at diagnosis.
Methods.
A retrospective review of 2,929 men diagnosed with prostate cancer was performed.
Pathological characteristics were compared across age groups: ≤55, 56–75, and >75 years.
Results.
The study cohort included 133 patients (4.5%), 2,033 patients (69.5%), and 763 patients (26.0%) in the three age groups, respectively.
The median pathological Gleason sums in the three age groups were 8, 7, and 8, respectively.
The Gleason sum, primary Gleason score, and second primary Gleason score were significantly different among the three age groups (Z=12.975, p=0.002; Z=9.264, p=0.010; Z=6.692, p=0.035, resp.).
The percentages of Gleason pattern 5 tumors for the three age groups were 44.4%, 32.3%, and 36.8%, respectively; they were significantly different (χ2=11.641, p=0.003).
The percentages of tumors with Gleason score grade groups 3–5 for the three age groups were 66.9%, 60.5%, and 66.3%, respectively; they were significantly different (χ2=9.401, p=0.009).
Conclusions.
The present study indicated that men aged ≤55 years or >75 years show higher levels of clinically significant prostate cancer compared to patients between the ages of 55 and 75 years.
Younger and more elderly male patients are more likely to have a more aggressive disease.
American Psychological Association (APA)
Ji, Guangjie& Huang, Cong& Song, Gang& Xiong, Gengyan& Fang, Dong& Wang, He…[et al.]. 2017. Are the Pathological Characteristics of Prostate Cancer More Aggressive or More Indolent Depending upon the Patient Age?. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1133931
Modern Language Association (MLA)
Ji, Guangjie…[et al.]. Are the Pathological Characteristics of Prostate Cancer More Aggressive or More Indolent Depending upon the Patient Age?. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1133931
American Medical Association (AMA)
Ji, Guangjie& Huang, Cong& Song, Gang& Xiong, Gengyan& Fang, Dong& Wang, He…[et al.]. Are the Pathological Characteristics of Prostate Cancer More Aggressive or More Indolent Depending upon the Patient Age?. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1133931
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133931