Meta-Analysis of the Potential Role of miRNA-21 in Cardiovascular System Function Monitoring
Joint Authors
Kozakiewicz, Mariusz
Krzywińska, Olga
Bracha, Marietta
Jeanniere, Caroline
Recchia, Emeline
Kędziora Kornatowska, Kornelia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-31
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
MicroRNAs (miRNAs) are short and noncoding RNA fragments that bind to the messenger RNA.
They have different roles in many physiological or pathological processes.
MicroRNA-21, one of the first miRNAs discovered, is encoded by the MIR21 gene and is located on the chromosomal positive strand 17q23.2.
MicroRNA-21 is transcribed by polymerase II and has its own promoter sequence, although it is in an intron.
It is intra- and extracellular and can be found in many body fluids, alone or combined with another molecule.
It regulates many signalling pathways and therefore plays an important role in the cardiovascular system.
Indeed, it is involved in the differentiation and migration of endothelial cells and angiogenesis.
It contributes to the reconstruction of a myocardial infarction, and it can also act as a cellular connector or as an antagonist to cardiac cell apoptosis.
By playing all these roles, it can be interesting to use it as a biomarker, especially for cardiovascular diseases.
American Psychological Association (APA)
Krzywińska, Olga& Bracha, Marietta& Jeanniere, Caroline& Recchia, Emeline& Kędziora Kornatowska, Kornelia& Kozakiewicz, Mariusz. 2020. Meta-Analysis of the Potential Role of miRNA-21 in Cardiovascular System Function Monitoring. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1133972
Modern Language Association (MLA)
Krzywińska, Olga…[et al.]. Meta-Analysis of the Potential Role of miRNA-21 in Cardiovascular System Function Monitoring. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1133972
American Medical Association (AMA)
Krzywińska, Olga& Bracha, Marietta& Jeanniere, Caroline& Recchia, Emeline& Kędziora Kornatowska, Kornelia& Kozakiewicz, Mariusz. Meta-Analysis of the Potential Role of miRNA-21 in Cardiovascular System Function Monitoring. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1133972
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133972