Human Papillomavirus Coinfection in the Cervical Intraepithelial Lesions and Cancer of Mexican Patients
Joint Authors
Padilla-Mendoza, Juan Ramón
Gómez-López, Lucía Angélica
López-Casamichana, Mavil
Azuara-Liceaga, Elisa Irene
Cortés-Malagón, Enoc Mariano
López-Cánovas, Lilia
Reyes-Hernández, Octavio Daniel
Rodríguez, Mario Alberto
Bonilla-Delgado, José
López-Reyes, Israel
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
According to their oncogenic properties, Human Papillomaviruses (HPVs) are classified into two types: Low-Risk (LR-HPVs) and High-Risk Human Papillomaviruses (HR-HPVs).
The immune system naturally controls the majority of HPV infections; however, when the HR-HPV infection is persistent, the risk of developing cervical cancer increases.
Previous studies indicate that multiple-infection or coinfection with HR-HPV occurs frequently and can potentiate the development of cervical lesions.
This study aimed to establish the HPV coinfection rate in squamous intraepithelial lesions from Mexican patients.
For HPV detection, we performed PCR on 55 cervical lesions diagnosed by colposcopy.
We detected the presence of HPV infection in 87.27% (48/55) of the lesions; interestingly, HPV coinfection was observed in 70.83% (34/48) of these samples.
We also evaluated HPV infection in adjacent areas without morphological changes from 25 samples.
The results showed that 80% (20/25) of these were HPV-positive and, curiously, all presented HPV-16 infection.
In conclusion, our results revealed a high prevalence of HPV coinfection in cervical lesions in Mexican patients, and these results contribute to future research focused on the role that HPV coinfection plays in the development of cervical cancer.
American Psychological Association (APA)
Padilla-Mendoza, Juan Ramón& Gómez-López, Lucía Angélica& López-Casamichana, Mavil& Azuara-Liceaga, Elisa Irene& Cortés-Malagón, Enoc Mariano& López-Cánovas, Lilia…[et al.]. 2020. Human Papillomavirus Coinfection in the Cervical Intraepithelial Lesions and Cancer of Mexican Patients. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1133987
Modern Language Association (MLA)
Padilla-Mendoza, Juan Ramón…[et al.]. Human Papillomavirus Coinfection in the Cervical Intraepithelial Lesions and Cancer of Mexican Patients. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1133987
American Medical Association (AMA)
Padilla-Mendoza, Juan Ramón& Gómez-López, Lucía Angélica& López-Casamichana, Mavil& Azuara-Liceaga, Elisa Irene& Cortés-Malagón, Enoc Mariano& López-Cánovas, Lilia…[et al.]. Human Papillomavirus Coinfection in the Cervical Intraepithelial Lesions and Cancer of Mexican Patients. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1133987
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1133987