Cerebral Venous Sinus Thrombosis and Hydrocephalus in a Vegan Secondary to Acquired Hyperhomocystinaemia
Joint Authors
Priyankara, W. D. D.
Chandimal, A.V. I.
Sivagnanam, F. G.
Manoj, E. M.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Cerebral venous sinus thrombosis associated with acute hydrocephalus and periventricular leukoencephalopathy is a challenging combination, in a critically ill with deteriorating neurology.
We report a case of a young man with acute onset neuropsychiatric manifestations, admitted to the intensive care unit.
He was found to have widespread cerebral venous sinus thrombosis, hyperintensities in basal ganglia, and acute hydrocephalus in magnetic resonance imaging, necessitating cerebrospinal fluid diversion, by way of an external ventricular drain and therapeutic anticoagulation.
He had otherwise normal routine biochemistry, except for macrocytosis, which prompted us to suspect acquired hyperhomocysteinemia secondary to cobalamin and folate deficiency, in the background of him being a vegan.
Replacement of vitamin B12, folic acid, pyridoxine along with anticoagulation and control of intracranial pressure with external ventricular drain lead to dramatic improvement of his neurology.
Therefore, high index of suspicion is crucial for a better outcome in otherwise irreversible neurological damage in acquired hyperhomocystinaemia.
American Psychological Association (APA)
Priyankara, W. D. D.& Chandimal, A.V. I.& Sivagnanam, F. G.& Manoj, E. M.. 2019. Cerebral Venous Sinus Thrombosis and Hydrocephalus in a Vegan Secondary to Acquired Hyperhomocystinaemia. Case Reports in Critical Care،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1134136
Modern Language Association (MLA)
Priyankara, W. D. D.…[et al.]. Cerebral Venous Sinus Thrombosis and Hydrocephalus in a Vegan Secondary to Acquired Hyperhomocystinaemia. Case Reports in Critical Care No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1134136
American Medical Association (AMA)
Priyankara, W. D. D.& Chandimal, A.V. I.& Sivagnanam, F. G.& Manoj, E. M.. Cerebral Venous Sinus Thrombosis and Hydrocephalus in a Vegan Secondary to Acquired Hyperhomocystinaemia. Case Reports in Critical Care. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1134136
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134136