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Comparisons of Efficacy of Intravitreal Aflibercept and Ranibizumab in Eyes with Diabetic Macular Edema
Joint Authors
Oshitari, Toshiyuki
Baba, Takayuki
Arai, Miyuki
Takatsuna, Yoko
Shimizu, Norihiro
Tatsumi, Tomoaki
Yamamoto, Shuichi
Sato, Eiju
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We compared the efficacy of intravitreal aflibercept (IVA) to intravitreal ranibizumab (IVR) injections in eyes with diabetic macular edema (DME).
The medical records of 49 eyes of 36 patients who were diagnosed with DME and had received IVR and 46 eyes of 40 patients who had received IVA treatment were reviewed.
The central macular thickness (CMT) and best-corrected visual acuity (BCVA) were measured at the baseline and at 1, 3, and 6 months after the IVR or IVA.
The mean number of injections of IVR was 2.6±1.1 and of IVA was 2.7±1.4.
At 6 months, the CMT was significantly thinner than the baseline after IVR and after IVA.
The mean BCVA was significantly better than the baseline after IVR only at 1 and 3 months and after IVA at 1 and 6 months.
The BCVA of eyes with serous retinal detachment (SRD) was significantly better at 1 month after the IVR and at 1 month and 6 months after the IVA.
The BCVAs improved more significantly in the SRD+ group than in the SRD− group.
The effects of IVA persist longer than that of IVR.
The effectiveness of both IVR and IVA was not dependent on the presence of SRD (IRB#2107).
American Psychological Association (APA)
Shimizu, Norihiro& Oshitari, Toshiyuki& Tatsumi, Tomoaki& Takatsuna, Yoko& Arai, Miyuki& Sato, Eiju…[et al.]. 2017. Comparisons of Efficacy of Intravitreal Aflibercept and Ranibizumab in Eyes with Diabetic Macular Edema. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134158
Modern Language Association (MLA)
Shimizu, Norihiro…[et al.]. Comparisons of Efficacy of Intravitreal Aflibercept and Ranibizumab in Eyes with Diabetic Macular Edema. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1134158
American Medical Association (AMA)
Shimizu, Norihiro& Oshitari, Toshiyuki& Tatsumi, Tomoaki& Takatsuna, Yoko& Arai, Miyuki& Sato, Eiju…[et al.]. Comparisons of Efficacy of Intravitreal Aflibercept and Ranibizumab in Eyes with Diabetic Macular Edema. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134158
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134158