Antibody-Based Immunotherapeutic Strategies for the Treatment of Hematological Malignancies
Joint Authors
Yan, Weiqi
Liu, Zhuojun
Xia, Yuanshi
Han, Yizhao
Yue, Shuhua
Yu, Jian
Liu, Jia
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
As the most common type of cancer in the world, hematological malignancies (HM) account for 10% of all annual cancer deaths and have attracted more attention.
Conventional treatments, such as chemotherapy, radiotherapy, and hematopoietic stem cell transplantation (HSCT), could relieve patients suffering HM.
However, serious side effects and high costs bring patients both physical complaints and mental pressure.
Recently, compared with conventional therapeutic strategies for HM patients, antibody-based immunotherapies, including cancer vaccines, oncolytic virus therapies, monoclonal antibody treatments, and CAR-T cell therapies, have displayed longer survival time and fewer adverse reactions, even though specific efficacy and safety of these antibody-based immunotherapies still need to be evaluated and improved.
This review summarized the advantages of antibody-based immunotherapies over conventional treatments, as well as its existing difficulties and solutions, thereby enhancing the understanding and applications of antibody-based immunotherapies in HM treatment.
American Psychological Association (APA)
Han, Yizhao& Liu, Zhuojun& Liu, Jia& Yan, Weiqi& Xia, Yuanshi& Yue, Shuhua…[et al.]. 2020. Antibody-Based Immunotherapeutic Strategies for the Treatment of Hematological Malignancies. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134345
Modern Language Association (MLA)
Han, Yizhao…[et al.]. Antibody-Based Immunotherapeutic Strategies for the Treatment of Hematological Malignancies. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1134345
American Medical Association (AMA)
Han, Yizhao& Liu, Zhuojun& Liu, Jia& Yan, Weiqi& Xia, Yuanshi& Yue, Shuhua…[et al.]. Antibody-Based Immunotherapeutic Strategies for the Treatment of Hematological Malignancies. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134345
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134345