Malnutrition-Related Factors Increased the Risk of Anastomotic Leak for Rectal Cancer Patients Undergoing Surgery

Joint Authors

Xu, Hao
Kong, Fanmin

Source

BioMed Research International

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-05-02

Country of Publication

Egypt

No. of Pages

6

Main Subjects

Medicine

Abstract EN

Objective.

To study the possible risk factors and related prediction indexes of anastomotic leakage (AL) in patients with rectal cancer during the perioperative period and to provide effective indexes for predicting whether AL will occur in postoperative patients with rectal cancer and whether early nutritional support is needed.

Background.

AL after rectal cancer surgery is a common and serious complication.

Many of the risk factors for AL have been confirmed.

Nevertheless, the evidence of the effect of perioperative malnutrition on AL is still insufficient.

This article will make a further study on this point.

Methods.

We collected perioperative clinical data from 382 patients with rectal cancer who underwent surgery from September 2015 to May 2017.

After 1 month of follow-up, relevant risk factor data were collected and analyzed.

Results.

Data analysis showed that the incidence of AL was 14.65%.

In single factor analysis, patients with high score of NRS-2002, high score of PG-SGA, diabetes, perioperative blood transfusion, postoperative diarrhea, later tumor stage, high score of ASA, low postoperative albumin, and rectal cancer patients with tumor close to the anus may led to AL.

Multivariate analysis revealed that low postoperative albumin (p=0.044), tumor close to the anus (p=0.004), diabetes (p=0.003), perioperative blood transfusion (p<0.001), diarrhea (p=0.005), later tumor stage, and high score of PG-SGA (p<0.001) were the independent risk factors for postoperative AL.

Conclusions.

AL in rectal cancer operation is a common postoperative complication.

Patients with diabetes or high PG-SGA score or low perioperative albumin will have increased risk factors of AL, which should be paid enough attention in the perioperative period and nutritional support should be provided as soon as possible.

Patients who have incomplete intestinal obstruction but can make effective intestinal preparation or who receive neoadjuvant chemotherapy have no increased risk of AL.

American Psychological Association (APA)

Xu, Hao& Kong, Fanmin. 2020. Malnutrition-Related Factors Increased the Risk of Anastomotic Leak for Rectal Cancer Patients Undergoing Surgery. BioMed Research International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1134425

Modern Language Association (MLA)

Xu, Hao& Kong, Fanmin. Malnutrition-Related Factors Increased the Risk of Anastomotic Leak for Rectal Cancer Patients Undergoing Surgery. BioMed Research International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1134425

American Medical Association (AMA)

Xu, Hao& Kong, Fanmin. Malnutrition-Related Factors Increased the Risk of Anastomotic Leak for Rectal Cancer Patients Undergoing Surgery. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1134425

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1134425