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Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient
Joint Authors
Giudice, Amerigo
Fortunato, L.
Bennardo, Francesco
Buffone, Caterina
Brancaccio, Ylenia
Plutino, Francesca Maria
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-27
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Angioleiomyoma (AL) is an uncommon benign soft tissue neoplasia arising from the tunica media of the smooth muscle cells.
AL appears as a solitary and slow-growing mass and seldom is observed in oral tissues.
We reported a rare case of AL involving the cheek of a 17-year-old young woman.
A review of the English-language literature was performed entering the keywords “angioleiomyoma” and “oral” in the search fields of PubMed.
70 results were identified.
Excluded were cases that were not in the oral cavity or not compatible with the AL diagnosis or report lacking immunohistochemical analysis.
According to the exclusion criteria, we selected 30 studies that included 63 cases of AL.
The results of the review showed an average age of 42.97 years with a prevalence between the fourth and fifth decade of life with a male-to-female ratio of 1.95 : 1.
The most affected sites were palate, buccal mucosa of the cheek, lip, tongue, and gingiva.
Surgical excision was the treatment of choice, and diagnosis was possible through histopathological and immunohistochemical analysis.
SMA, vimentin, CD34, desmin, and S-100 were the most common markers to guide the histopathological diagnosis of oral AL.
In conclusion, oral AL is a rare entity, especially in adolescence as in the reported case of AL of the cheek in a 17-year-old woman.
The clinical aspects of AL did not allow clinicians to make a correct presumptive diagnosis.
A scrupulous histopathological analysis and immunohistochemical examinations are fundamental to differentiate AL from other lesions.
American Psychological Association (APA)
Giudice, Amerigo& Bennardo, Francesco& Buffone, Caterina& Brancaccio, Ylenia& Plutino, Francesca Maria& Fortunato, L.. 2019. Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient. Case Reports in Dentistry،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1134447
Modern Language Association (MLA)
Giudice, Amerigo…[et al.]. Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient. Case Reports in Dentistry No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1134447
American Medical Association (AMA)
Giudice, Amerigo& Bennardo, Francesco& Buffone, Caterina& Brancaccio, Ylenia& Plutino, Francesca Maria& Fortunato, L.. Clinical and Immunohistochemical Features of Oral Angioleiomyoma: A Comprehensive Review of the Literature and Report of a Case in a Young Patient. Case Reports in Dentistry. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1134447
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134447