Periodontal Disease and Tooth Loss Are Associated with Lung Cancer Risk
Joint Authors
Chen, You
Zhu, Bao-ling
Wu, Cong-cong
Lin, Rui-fang
Zhang, Xi
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
The associations between periodontal disease, tooth loss, and lung cancer risk remain debatable.
Therefore, the purpose of the present study is to evaluate whether periodontal disease and tooth loss are associated with lung cancer risk.
Methods.
A literature search was performed for relevant studies using PubMed and Embase databases.
Risk ratio (RR) with 95% confidence interval (CI) was applied as effect size to summarize the associations between periodontal disease, tooth loss, and lung cancer risk.
A further dose-response analysis was also performed.
Results.
A total of twelve studies comprising 263,238 participants were included.
The results indicated that periodontal disease was positively associated with lung cancer risk (RR=1.37, 95%CI=1.16‐1.63).
There was a positive association between tooth loss and lung cancer risk (RR=1.69, 95%CI=1.46‐1.96).
Moreover, there was a significantly linear dose-response relationship between tooth loss and lung cancer risk, and every 5 increment in tooth loss was associated with 10% increased lung cancer risk.
Similar results were obtained in subgroup analysis.
Conclusions.
Periodontal disease and tooth loss are increased risk factors for lung cancer.
Prevention and treatment of periodontal disease may be effective potential prevention strategies for lung cancer.
American Psychological Association (APA)
Chen, You& Zhu, Bao-ling& Wu, Cong-cong& Lin, Rui-fang& Zhang, Xi. 2020. Periodontal Disease and Tooth Loss Are Associated with Lung Cancer Risk. BioMed Research International،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1134502
Modern Language Association (MLA)
Chen, You…[et al.]. Periodontal Disease and Tooth Loss Are Associated with Lung Cancer Risk. BioMed Research International No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1134502
American Medical Association (AMA)
Chen, You& Zhu, Bao-ling& Wu, Cong-cong& Lin, Rui-fang& Zhang, Xi. Periodontal Disease and Tooth Loss Are Associated with Lung Cancer Risk. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1134502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134502