Identification and Expression Pattern of EZH2 in Pig Developing Fetuses
Joint Authors
Gu, Ting
Tan, Baohua
Hong, Linjun
Qiao, Jiaxin
Zhou, Jian
Xing, Pingping
Yan, Guanhao
Zheng, Enqin
Cai, Gengyuan
Huang, Sixiu
Wu, Zhenfang
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The proper methylation status of histones is essential for appropriate cell lineage and organogenesis.
EZH2, a methyltransferase catalyzing H3K27me3, has been abundantly studied in human and mouse embryonic development.
The pig is an increasing important animal model for molecular study and pharmaceutical research.
However, the transcript variant and temporal expression pattern of EZH2 in the middle and late porcine fetus are still unknown.
Here, we identified the coding sequence of the EZH2 gene and characterized its expression pattern in fetal tissues of Duroc pigs at 65- and 90-day postcoitus (dpc).
Our results showed that the coding sequence of EZH2 was 2241 bp, encoding 746 amino acids.
There were 9 amino acid insertions and an amino acid substitution in this transcript compared with the validated reference sequence in NCBI.
EZH2 was ubiquitously expressed in the fetal tissues of two time points with different expression levels.
These results validated a different transcript in pigs and characterized its expression profile in fetal tissues of different gestation stages, which indicated that EZH2 played important roles during porcine embryonic development.
American Psychological Association (APA)
Tan, Baohua& Hong, Linjun& Qiao, Jiaxin& Zhou, Jian& Xing, Pingping& Yan, Guanhao…[et al.]. 2020. Identification and Expression Pattern of EZH2 in Pig Developing Fetuses. BioMed Research International،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1134684
Modern Language Association (MLA)
Tan, Baohua…[et al.]. Identification and Expression Pattern of EZH2 in Pig Developing Fetuses. BioMed Research International No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1134684
American Medical Association (AMA)
Tan, Baohua& Hong, Linjun& Qiao, Jiaxin& Zhou, Jian& Xing, Pingping& Yan, Guanhao…[et al.]. Identification and Expression Pattern of EZH2 in Pig Developing Fetuses. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1134684
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134684