Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells
Joint Authors
Sun, Lining
Zhu, Botao
Li, Wanting
Zhu, Mingjie
Hsu, Po-Lin
Yang, Hao
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-06
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The mechanical properties of cells are closely related to their physiological functions and states.
Analyzing and measuring these properties are beneficial to understanding cell mechanisms.
However, most measurement methods only involve the unidirectional analysis of cellular mechanical properties and thus result in the incomplete measurement of these properties.
In this study, a microfluidic platform was established, and an innovative microfluidic chip was designed to measure the multiangle cellular mechanical properties by using dielectrophoresis (DEP) force.
Three unsymmetrical indium tin oxide (ITO) microelectrodes were designed and combined with the microfluidic chip, which were utilized to generate DEP force and stretch cell from different angles.
A series of experiments was performed to measure and analyze the multiangle mechanical properties of red blood cells of mice.
This work provided a new tool for the comprehensive and accurate measurement of multiangle cellular mechanical properties.
The results may contribute to the exploration of the internal physiological structures of cells and the building of accurate cell models.
American Psychological Association (APA)
Zhu, Botao& Li, Wanting& Zhu, Mingjie& Hsu, Po-Lin& Sun, Lining& Yang, Hao. 2020. Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134721
Modern Language Association (MLA)
Zhu, Botao…[et al.]. Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1134721
American Medical Association (AMA)
Zhu, Botao& Li, Wanting& Zhu, Mingjie& Hsu, Po-Lin& Sun, Lining& Yang, Hao. Dielectrophoresis-Based Method for Measuring the Multiangle Mechanical Properties of Biological Cells. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134721
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134721