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Chinese Herbal Medicine Dingji Fumai Decoction for Ventricular Premature Contraction: A Real-World Trial
Joint Authors
Liang, Bo
Zou, Fei-Hu
Fu, Ling
Liao, Hui-Ling
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-09
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Chinese herbal medicine Dingji Fumai Decoction (DFD) is widely clinically used for ventricular premature contraction (VPC).
This real-word trial was designed to assess the safety and effectiveness of DFD for VPC.
Methods.
This was a double-blinded, randomized placebo-controlled trial.
Patients with VPC were randomized (1 : 1) to treatment with DFD combined with metoprolol (DFD arm) or metoprolol combined with placebo (MET arm).
A primary end point was a composite of clinical symptoms and signs determined by the traditionalChinese medicine syndrome score and the number of VPC determined by the Holter examination.
Second outcomes were adverse events, medication compliance, and laboratory examination.
Results.
144 patients were randomized to DFD arm (76 patients) or MET arm (68 patients), and 136 cases (71 in DFD arm and 65 in MET arm) finally completed this trial.
After a 12-week follow-up, DFD arm significantly decreased traditional Chinese medicine syndrome score and the number of VPC compared with MET arm (P=0.003 and 0.034, respectively).
There was no adverse drug effect and patient medication compliance was good.
Conclusions.
Superiority with DFD arm for VPC was demonstrated over MET arm for both the safety and effectiveness end points.
American Psychological Association (APA)
Liang, Bo& Zou, Fei-Hu& Fu, Ling& Liao, Hui-Ling. 2020. Chinese Herbal Medicine Dingji Fumai Decoction for Ventricular Premature Contraction: A Real-World Trial. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1134725
Modern Language Association (MLA)
Liang, Bo…[et al.]. Chinese Herbal Medicine Dingji Fumai Decoction for Ventricular Premature Contraction: A Real-World Trial. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1134725
American Medical Association (AMA)
Liang, Bo& Zou, Fei-Hu& Fu, Ling& Liao, Hui-Ling. Chinese Herbal Medicine Dingji Fumai Decoction for Ventricular Premature Contraction: A Real-World Trial. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1134725
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134725