TriglycerideHigh-Density Lipoprotein Cholesterol Ratio Is Associated with In-Hospital Mortality in Acute Type B Aortic Dissection

Abstract EN

Background.

Triglyceride/high-density lipoprotein cholesterol (TG/HDL-c) ratio varies with vascular and other metabolic diseases.

However, its role in acute type B aortic dissection is not well understood.

In the current study, we evaluated the relationship between TG/HDL-c ratio and in-hospital mortality in type B aortic dissection.

Methods.

We performed a retrospective analysis of consecutive patients between January 2015 and December 2018, by targeting dependent (TG/HDL-c ratio) and independent (in-hospital mortality) variables.

TG/HDL-c ratio was determined as a division of TG levels by HDL-c levels.

Results.

Of 523 patients in the study, we found a mean age of 55.00±11.74 years, 15.68% of them being female.

A fully-adjusted model revealed a positive relationship between TG/HDL-c ratio and in-hospital mortality in acute type B aortic dissection after adjusting confounders (OR=2.08, 95% CI 1.32 to 3.27).

This relationship was also nonlinear, with a point of 2.05.

OR values (and confidence intervals) for the right (>2.05) and left (≤2.05) sides of the inflection point were 1.0 (0.580-1.26, P=0.983) and 3.17 (1.54-6.57, P=0.001), respectively.

Conclusions.

The TG/HDL-c ratio and in-hospital mortality in type B AAD have a nonlinear relationship among Chinese population.

This ratio increased in-hospital mortality when it is less than 2.05.