Roles and Clinical Applications of Exosomes in Cardiovascular Disease

Joint Authors

Xu, Yuerong
Zhang, Mingming
Guo, Dong
Ding, Jian
Dong, Jiaying
Jia, Ning
Li, Yan

Source

BioMed Research International

Issue

Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2020-06-10

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Medicine

Abstract EN

Despite substantial improvements in therapeutic strategies, cardiovascular disease (CVD) is still among the leading causes of mortality and morbidity worldwide.

Exosomes, extracellular vesicles with a lipid bilayer membrane of endosomal origin, have been the focus of a large body of research in CVD.

Exosomes not only serve as carriers for signal molecules responsible for intercellular and interorgan communication underlying CVD pathophysiology but also are bioactive agents which are partly responsible for the therapeutic effect of stem cell therapy of CVD.

We here review recent insights gained into the role of exosomes in apoptosis, hypertrophy, angiogenesis, fibrosis, and inflammation in CVD pathophysiology and progression and the application and mechanisms of exosomes as therapeutic agents for CVD.

American Psychological Association (APA)

Guo, Dong& Xu, Yuerong& Ding, Jian& Dong, Jiaying& Jia, Ning& Li, Yan…[et al.]. 2020. Roles and Clinical Applications of Exosomes in Cardiovascular Disease. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134761

Modern Language Association (MLA)

Guo, Dong…[et al.]. Roles and Clinical Applications of Exosomes in Cardiovascular Disease. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1134761

American Medical Association (AMA)

Guo, Dong& Xu, Yuerong& Ding, Jian& Dong, Jiaying& Jia, Ning& Li, Yan…[et al.]. Roles and Clinical Applications of Exosomes in Cardiovascular Disease. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134761

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1134761