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Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation
Joint Authors
Liu, Song
Xing, Ronge
Li, Pengcheng
Qin, Yukun
Li, Kecheng
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-05
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Chitohexaose has attracted wide interest due to its special bioactivities and these potential activities are significantly related to N-acetylation.
Herein, six chitohexaose fractions with different degrees of acetylation were prepared by selective N-acetylation and ion-exchange chromatography and further analyzed by ESI/MS.
It is revealed that all the six N-acetylated chitohexaoses were of single molecular weight, the molecular weights of which were exactly assigned to 1026.44 Da, 1068.44 Da, 1110.48 Da, 1152.48 Da, 1194.49 Da, and 1236.48 Da, respectively.
These results suggested that the six prepared N-acetylated chitohexaoses were N-acetylchitohexaose (D5A1), di-N-acetylchitohexaose (D4A2), tri-N-acetylchitohexaose (D3A3), tetra-N-acetylchitohexaose (D2A4), penta-N-acetylchitohexaose (D1A5), and hexa-N-acetylchitohexaose (A6), respectively, which are of great significance to screen their bioactivities and discover well-defined chitooligosaccharide molecules as potential drugs.
American Psychological Association (APA)
Li, Kecheng& Xing, Ronge& Liu, Song& Qin, Yukun& Li, Pengcheng. 2017. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation. BioMed Research International،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1134820
Modern Language Association (MLA)
Li, Kecheng…[et al.]. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation. BioMed Research International No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1134820
American Medical Association (AMA)
Li, Kecheng& Xing, Ronge& Liu, Song& Qin, Yukun& Li, Pengcheng. Access to N-Acetylated Chitohexaose with Well-Defined Degrees of Acetylation. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1134820
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134820