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Hyperphosphatemia and hs-CRP Initiate the Coronary Artery Calcification in Peritoneal Dialysis Patients
Joint Authors
Shang, Da
Xie, Qionghong
Shang, Bin
Zhang, Min
You, Li
Hao, Chuan-Ming
Zhu, Tongying
Source
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Coronary artery calcification (CAC) contributes to high risk of cardiocerebrovascular diseases in dialysis patients.
However, the risk factors for CAC initiation in peritoneal dialysis (PD) patients are not known clearly.
Methods.
Adult patients with baseline CaCS = 0 and who were followed up for at least 3 years or until the conversion from absent to any measurable CAC detected were included in this observational cohort study.
Binary logistic regression was performed to identify the risk factors for CAC initiation in PD patients.
Results.
70 patients recruited to our study were split into a noninitiation group (n=37) and an initiation group (n=33) according to the conversion of any measurable CAC during their follow-up or not.
In univariate analysis, systolic blood pressure, serum phosphorus, fibrinogen, hs-CRP, serum creatinine, and triglycerides were positively associated with the initiation of CAC, while the high density lipoprotein and nPCR did the opposite function.
Multivariate analysis revealed that hyperphosphatemia and hs-CRP were the independent risk factors for CAC initiation after adjustments.
Conclusions.
Hyperphosphatemia and hs-CRP were the independent risk factors for CAC initiation in PD patients.
These results suggested potential clinical strategies to prevent the initiation of CAC in PD patients.
American Psychological Association (APA)
Shang, Da& Xie, Qionghong& Shang, Bin& Zhang, Min& You, Li& Hao, Chuan-Ming…[et al.]. 2017. Hyperphosphatemia and hs-CRP Initiate the Coronary Artery Calcification in Peritoneal Dialysis Patients. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134873
Modern Language Association (MLA)
Shang, Da…[et al.]. Hyperphosphatemia and hs-CRP Initiate the Coronary Artery Calcification in Peritoneal Dialysis Patients. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1134873
American Medical Association (AMA)
Shang, Da& Xie, Qionghong& Shang, Bin& Zhang, Min& You, Li& Hao, Chuan-Ming…[et al.]. Hyperphosphatemia and hs-CRP Initiate the Coronary Artery Calcification in Peritoneal Dialysis Patients. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1134873
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134873