The Neutrophil Percentage-to-Albumin Ratio Is Associated with All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury
Joint Authors
Wang, Benji
Gong, Yuqiang
Ying, Binyu
Cheng, Bihuan
Li, Diwen
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
There is no evidence to suggest the predictive power of neutrophil percentage-to-albumin ratio (NPAR) in patients with acute kidney injury (AKI).
We hypothesized that NPAR would correlate with all-cause mortality in critically ill patients with AKI.
Methods.
From the MIMIC-III V1.4 database, we extracted demographics, vital signs, comorbidities, laboratory tests, and other clinical data.
The clinical endpoints were 30-, 90- and 365-day all-cause mortality in critically ill patients with AKI.
Cox proportional hazards models were used to evaluate the prognostic values of NPAR, and subgroup analyses were performed to measure mortality across various subgroups.
Results.
A total of 7,481 eligible subjects were enrolled.
In multivariate analysis, after adjustments for age, ethnicity, gender, and other confounding factors, higher NPARs were associated with an increased risk of 30-, 90- and 365-day all-cause mortality in critically ill patients with AKI (tertile 3 versus tertile 1: adjusted HR, 95% CI: 1.48, 1.30–1.69; 1.47, 1.31–1.66; 1.46, 1.32–1.62, respectively; P trend <0.01).
A similar trend was observed in the NPAR group division by quintiles.
Subgroup analysis revealed no significant interactions in most strata.
Conclusions.
Increased NPAR correlates with increased risk of all-cause mortality in critically ill patients with AKI.
American Psychological Association (APA)
Wang, Benji& Li, Diwen& Cheng, Bihuan& Ying, Binyu& Gong, Yuqiang. 2020. The Neutrophil Percentage-to-Albumin Ratio Is Associated with All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134879
Modern Language Association (MLA)
Wang, Benji…[et al.]. The Neutrophil Percentage-to-Albumin Ratio Is Associated with All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1134879
American Medical Association (AMA)
Wang, Benji& Li, Diwen& Cheng, Bihuan& Ying, Binyu& Gong, Yuqiang. The Neutrophil Percentage-to-Albumin Ratio Is Associated with All-Cause Mortality in Critically Ill Patients with Acute Kidney Injury. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1134879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134879