Probiotics Used for Postoperative Infections in Patients Undergoing Colorectal Cancer Surgery
Joint Authors
Chen, Chongxiang
Wen, Tianmeng
Zhao, Qingyu
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
The objective of this study was to conduct a systematic review and meta-analysis about probiotics to improve postoperative infections in patients undergoing colorectal cancer surgery.
Methods.
The PubMed and the Web of Science were used to search for appropriate randomized clinical trials (RCTs) comparing probiotics with placebo for the patients undergoing colorectal cancer surgery.
The RevMan 5.3 was performed for meta-analysis to evaluate the postoperative infection, including the total infection, surgical site infection, central line infection, pneumonia, urinary tract infection, septicemia, and postoperative leakage.
Results.
Our meta-analysis included 6 studies involving a total of 803 patients.
For the incidence of total postoperative infection (odd ratios (OR) 0.31, 95% confidence interval (CI) 0.15–0.64, I 2 =0%), surgical site infection (OR 0.62, 95% CI 0.39–0.99, I 2 =11%), central line infection (OR 0.61, 95% CI 0.15–2.45, I 2 =65%), pneumonia (OR 0.36, 95% CI 0.18–0.71, I 2 =0%), urinary tract infection (OR 0.26, 95% CI 0.11–0.60, I 2 =26%), septicemia (OR 0.28, 95% CI 0.17–0.49, I 2 =10%), postoperative leakage (OR 0.45, 95% CI 0.06–3.27, I 2 =68%), the results showed that the incidences of infections were significantly lower in the probiotics group than the placebo group.
Conclusions.
Probiotics is beneficial to prevent postoperative infections (including total postoperative infection, surgical site infection, pneumonia, urinary tract infection, and septicemia) in patients with colorectal cancer.
American Psychological Association (APA)
Chen, Chongxiang& Wen, Tianmeng& Zhao, Qingyu. 2020. Probiotics Used for Postoperative Infections in Patients Undergoing Colorectal Cancer Surgery. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134899
Modern Language Association (MLA)
Chen, Chongxiang…[et al.]. Probiotics Used for Postoperative Infections in Patients Undergoing Colorectal Cancer Surgery. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1134899
American Medical Association (AMA)
Chen, Chongxiang& Wen, Tianmeng& Zhao, Qingyu. Probiotics Used for Postoperative Infections in Patients Undergoing Colorectal Cancer Surgery. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1134899
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134899