Research Advances in the Mechanisms of Hyperuricemia-Induced Renal Injury
Joint Authors
Liu, Hua-feng
Su, Hong-yong
Yang, Chen
Liang, Dong
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-27
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Uric acid is the end product of purine metabolism in humans, and its excessive accumulation leads to hyperuricemia and urate crystal deposition in tissues including joints and kidneys.
Hyperuricemia is considered an independent risk factor for cardiovascular and renal diseases.
Although the symptoms of hyperuricemia-induced renal injury have long been known, the pathophysiological molecular mechanisms are not completely understood.
In this review, we focus on the research advances in the mechanisms of hyperuricemia-caused renal injury, primarily on oxidative stress, endothelial dysfunction, renal fibrosis, and inflammation.
Furthermore, we discuss the progress in hyperuricemia management.
American Psychological Association (APA)
Su, Hong-yong& Yang, Chen& Liang, Dong& Liu, Hua-feng. 2020. Research Advances in the Mechanisms of Hyperuricemia-Induced Renal Injury. BioMed Research International،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1134964
Modern Language Association (MLA)
Su, Hong-yong…[et al.]. Research Advances in the Mechanisms of Hyperuricemia-Induced Renal Injury. BioMed Research International No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1134964
American Medical Association (AMA)
Su, Hong-yong& Yang, Chen& Liang, Dong& Liu, Hua-feng. Research Advances in the Mechanisms of Hyperuricemia-Induced Renal Injury. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1134964
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1134964